Evolutionary footprints of nucleosome positions in yeast. Export

@article{citeulike:3578464, abstract = {Using genome-wide maps of nucleosome positions in yeast, we have analyzed the influence of chromatin structure on the molecular evolution of genomic DNA. We have observed, on average, 10-15\% lower substitution rates in linker regions than in nucleosomal DNA. This widespread local rate heterogeneity represents an evolutionary footprint of nucleosome positions and reveals that nucleosome organization is a genomic feature conserved over evolutionary timescales.}, author = {Washietl, S. and Machne, R. and Goldman, N.}, citeulike-article-id = {3578464}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.tig.2008.09.003}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0168952508002552}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/18951646}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=18951646}, citeulike-linkout-4 = {http://dx.doi.org/http://dx.doi.org/10.1016/j.tig.2008.09.003}, citeulike-linkout-5 = {http://dx.doi.org/10.1016/j.tig.2008.09.003}, day = {24}, doi = {10.1016/j.tig.2008.09.003}, issn = {0168-9525}, journal = {Trends in genetics : TIG}, keywords = {goldmanlab}, month = {October}, number = {12}, pages = {583--587}, posted-at = {2008-12-04 14:54:20}, priority = {2}, title = {Evolutionary footprints of nucleosome positions in yeast.}, url = {http://dx.doi.org/10.1016/j.tig.2008.09.003}, volume = {24}, year = {2008} }

TY - JOUR ID - citeulike:3578464 L3 - citeulike-article-id:3578464 N2 - Using genome-wide maps of nucleosome positions in yeast, we have analyzed the influence of chromatin structure on the molecular evolution of genomic DNA. We have observed, on average, 10-15% lower substitution rates in linker regions than in nucleosomal DNA. This widespread local rate heterogeneity represents an evolutionary footprint of nucleosome positions and reveals that nucleosome organization is a genomic feature conserved over evolutionary timescales. IS - 12 JF - Trends in genetics : TIG SN - 0168-9525 EP - 587 TI - Evolutionary footprints of nucleosome positions in yeast. VL - 24 SP - 583 KW - goldmanlab AU - Washietl, S AU - Machne, R AU - Goldman, N PY - 2008/October/24/ UR - http://dx.doi.org/10.1016/j.tig.2008.09.003 ER -