Structural biology and phylogenetic estimation Export

@article{citeulike:5815965, abstract = {When reconstructing evolutionary trees from DNA sequences, it is often assumed that increasing the amount of sequence will improve the phylogenetic estimate1, 2. This is based on the notion that historical 'signal' will rise above misleading 'noise' as more sequence is gathered. Our analysis of mitochondrial genomes fails to support this assumption, but suggests a way to select objectively for data with maximum 'signal-to-noise' potential.}, author = {Naylor, Gavin J. P. and Brown, Wesley M.}, citeulike-article-id = {5815965}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/41460}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/388527a0}, day = {07}, doi = {10.1038/41460}, issn = {0028-0836}, journal = {Nature}, keywords = {phylogenetics, proteins}, month = {August}, number = {6642}, pages = {527--528}, posted-at = {2009-09-21 19:40:31}, priority = {2}, publisher = {Nature Publishing Group}, title = {Structural biology and phylogenetic estimation}, url = {http://dx.doi.org/10.1038/41460}, volume = {388}, year = {1997} }

TY - JOUR ID - citeulike:5815965 L3 - citeulike-article-id:5815965 N2 - When reconstructing evolutionary trees from DNA sequences, it is often assumed that increasing the amount of sequence will improve the phylogenetic estimate1, 2. This is based on the notion that historical 'signal' will rise above misleading 'noise' as more sequence is gathered. Our analysis of mitochondrial genomes fails to support this assumption, but suggests a way to select objectively for data with maximum 'signal-to-noise' potential. IS - 6642 JF - Nature SN - 0028-0836 EP - 528 TI - Structural biology and phylogenetic estimation PB - Nature Publishing Group VL - 388 SP - 527 KW - phylogenetics KW - proteins AU - Naylor, Gavin AU - Brown, Wesley PY - 1997/08/07/ UR - http://dx.doi.org/10.1038/41460 ER -