Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure Export

@article{citeulike:4400979, abstract = {A method is proposed that finds enriched pathways relevant to a studied condition using the measured molecular data and also the structural information of the pathway viewed as a network of nodes and edges. Tests are performed using simulated data and genomic data sets and the method is compared to two existing approaches. The analysis provided demonstrates the method proposed is very competitive with the current approaches and also provides biologically relevant results.}, author = {Thomas, Reuben and Gohlke, Julia and Stopper, Geffrey and Parham, Frederick and Portier, Christopher}, citeulike-article-id = {4400979}, citeulike-linkout-0 = {http://dx.doi.org/10.1186/gb-2009-10-4-r44}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/19393085}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=19393085}, day = {24}, doi = {10.1186/gb-2009-10-4-r44}, issn = {1465-6906}, journal = {Genome Biology}, keywords = {analysis, microarrays, network, pathway}, month = {April}, number = {4}, pages = {R44+}, posted-at = {2009-10-11 02:01:52}, priority = {2}, title = {Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure}, url = {http://dx.doi.org/10.1186/gb-2009-10-4-r44}, volume = {10}, year = {2009} }

TY - JOUR ID - citeulike:4400979 L3 - citeulike-article-id:4400979 N2 - A method is proposed that finds enriched pathways relevant to a studied condition using the measured molecular data and also the structural information of the pathway viewed as a network of nodes and edges. Tests are performed using simulated data and genomic data sets and the method is compared to two existing approaches. The analysis provided demonstrates the method proposed is very competitive with the current approaches and also provides biologically relevant results. IS - 4 JF - Genome Biology SN - 1465-6906 TI - Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure VL - 10 SP - R44 KW - analysis KW - microarrays KW - network KW - pathway AU - Thomas, Reuben AU - Gohlke, Julia AU - Stopper, Geffrey AU - Parham, Frederick AU - Portier, Christopher PY - 2009/04/24/ UR - http://dx.doi.org/10.1186/gb-2009-10-4-r44 ER -