Cervical vertebral malformation-malarticulation syndrome in the Bernese mountain dog: clinical and magnetic resonance imaging features Export

@article{citeulike:4201119, abstract = {Objectives: To describe the clinical and magnetic resonance imaging features of cervical vertebral malformation-malarticulation in Bernese mountain dogs.Methods: Seven Bernese mountain dogs (four males and three females) were diagnosed with cervical vertebral malformation-malarticulation by magnetic resonance imaging. The following data were evaluated retrospectively: (1) abnormalities of the cervical vertebral column and spinal cord, (2) spinal cord compression, (3) intervertebral disc degeneration and herniation, (4) severity of clinical signs pretreatment and after treatment, (5) type of treatment and (6) outcome.Results: Spin echo T1-weighted and T2-weighted images disclosed multi-level, extradural compressive spinal cord lesions (ventral, dorsolateral or both) spanning from intervertebral disc spaces C3-4 to C6-7. In all seven dogs, T2-weighted images disclosed one or more intramedullary hyperintensities associated with extradural spinal cord compression. Surgery was performed in five dogs. Two dogs were managed medically. The prognosis for surgical or conservative management in Bernese mountain dogs was similar to cervical vertebral malformation-malarticulation in other breeds.Clinical Significance: Cervical vertebral malformation-malarticulation is an important differential diagnosis for young to middle-aged Bernese mountain dogs with a C1-5 or C6-T2 neuroanatomic localisation. Dorsolateral spinal cord compression associated with articular process hypertrophy was the most common feature of cervical vertebral malformation-malarticulation in the seven Bernese mountain dogs evaluated.}, address = {Canada West Veterinary Specialists, 1988 Kootenay Street, Vancouver, BC, Canada V5M 4Y3; Department of Veterinary Small Animal Clinical Sciences, Texas A\&M University College of Veterinary Medicine, College Station, TX 77843, USA}, author = {Eagleson, J. S. and Diaz, J. and Platt, S. R. and Kent, M. and Levine, J. M. and Sharp, N. J. H. and Schatzberg, S. J.}, citeulike-article-id = {4201119}, citeulike-linkout-0 = {http://dx.doi.org/10.1111/j.1748-5827.2009.00731.x}, citeulike-linkout-1 = {http://www.ingentaconnect.com/content/bsc/jsap/2009/00000050/00000004/art00006}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/19320813}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=19320813}, citeulike-linkout-4 = {http://www3.interscience.wiley.com/cgi-bin/abstract/122262920/ABSTRACT}, doi = {10.1111/j.1748-5827.2009.00731.x}, issn = {1748-5827}, journal = {Journal of Small Animal Practice}, keywords = {cervical, malarticulation, malformation, mri, vertebra}, number = {4}, pages = {186--193}, posted-at = {2009-04-21 22:53:44}, priority = {2}, publisher = {Blackwell Publishing}, title = {Cervical vertebral malformation-malarticulation syndrome in the Bernese mountain dog: clinical and magnetic resonance imaging features}, url = {http://dx.doi.org/10.1111/j.1748-5827.2009.00731.x}, volume = {50}, year = {2009} }

TY - JOUR ID - citeulike:4201119 L3 - citeulike-article-id:4201119 N2 - Objectives: To describe the clinical and magnetic resonance imaging features of cervical vertebral malformation-malarticulation in Bernese mountain dogs.Methods: Seven Bernese mountain dogs (four males and three females) were diagnosed with cervical vertebral malformation-malarticulation by magnetic resonance imaging. The following data were evaluated retrospectively: (1) abnormalities of the cervical vertebral column and spinal cord, (2) spinal cord compression, (3) intervertebral disc degeneration and herniation, (4) severity of clinical signs pretreatment and after treatment, (5) type of treatment and (6) outcome.Results: Spin echo T1-weighted and T2-weighted images disclosed multi-level, extradural compressive spinal cord lesions (ventral, dorsolateral or both) spanning from intervertebral disc spaces C3-4 to C6-7. In all seven dogs, T2-weighted images disclosed one or more intramedullary hyperintensities associated with extradural spinal cord compression. Surgery was performed in five dogs. Two dogs were managed medically. The prognosis for surgical or conservative management in Bernese mountain dogs was similar to cervical vertebral malformation-malarticulation in other breeds.Clinical Significance: Cervical vertebral malformation-malarticulation is an important differential diagnosis for young to middle-aged Bernese mountain dogs with a C1-5 or C6-T2 neuroanatomic localisation. Dorsolateral spinal cord compression associated with articular process hypertrophy was the most common feature of cervical vertebral malformation-malarticulation in the seven Bernese mountain dogs evaluated. IS - 4 JF - Journal of Small Animal Practice SN - 1748-5827 AD - Canada West Veterinary Specialists, 1988 Kootenay Street, Vancouver, BC, Canada V5M 4Y3; Department of Veterinary Small Animal Clinical Sciences, Texas A&M University College of Veterinary Medicine, College Station, TX 77843, USA EP - 193 TI - Cervical vertebral malformation-malarticulation syndrome in the Bernese mountain dog: clinical and magnetic resonance imaging features PB - Blackwell Publishing VL - 50 SP - 186 KW - cervical KW - malarticulation KW - malformation KW - mri KW - vertebra AU - Eagleson, JS AU - Diaz, J AU - Platt, SR AU - Kent, M AU - Levine, JM AU - Sharp, NJH AU - Schatzberg, SJ PY - 2009/// UR - http://dx.doi.org/10.1111/j.1748-5827.2009.00731.x ER -