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PERMORY-MPI: A program for high-speed parallel permutation testing in genome-wide association studies

by: Volker Steiß, Thomas Letschert, Helmut Schäfer, Roman Pahl
Bioinformatics, Vol. 28, No. 8. (17 February 2012), pp. 1168-1169, doi:10.1093/bioinformatics/bts086  Key: citeulike:10392310

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Abstract

Summary: PERMORY (Pahl and Schäfer, 2010) is software for accelerated permutation testing of genome-wide association studies GWAS). We have parallelized PERMORY using the Message-Passing Interface resulting in a nearly linear speedup. Furthermore, we added accelerated analysis of GWAS using quantitative phenotypes, and an accurate estimation of the effective number of independent tests.


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