Impact of obesity, steatosis and insulin resistance on progression and response to therapy of hepatitis C. Export

@article{citeulike:5814936, abstract = {Clinical progression of chronic hepatitis C depends on several cofactors, which also have a negative affect on the rate of response to interferon-alpha-based therapy. Given the current worldwide prevalence of the metabolic syndrome, the impact of obesity and insulin resistance, and of their histopathological correlate, hepatic steatosis, on the natural history and management of chronic hepatitis C is undoubtedly very important. We will review some of the current knowledge on the clinical consequences of overweight/obesity, steatosis and insulin resistance on chronic hepatitis C, and discuss how this issue may be dealt with in clinical practice.}, author = {Negro, F. and Cl\'{e}ment, S.}, citeulike-article-id = {5814936}, citeulike-linkout-0 = {http://dx.doi.org/10.1111/j.1365-2893.2009.01186.x}, citeulike-linkout-1 = {http://www.ingentaconnect.com/content/bsc/jvh/2009/00000016/00000010/art00001}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/19732324}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=19732324}, doi = {10.1111/j.1365-2893.2009.01186.x}, issn = {1365-2893}, journal = {Journal of viral hepatitis}, keywords = {hcv, irs, nash, obesity}, month = {October}, number = {10}, pages = {681--688}, posted-at = {2009-11-04 04:14:36}, priority = {2}, publisher = {Blackwell Publishing}, title = {Impact of obesity, steatosis and insulin resistance on progression and response to therapy of hepatitis C.}, url = {http://dx.doi.org/10.1111/j.1365-2893.2009.01186.x}, volume = {16}, year = {2009} }

TY - JOUR ID - citeulike:5814936 L3 - citeulike-article-id:5814936 N2 - Clinical progression of chronic hepatitis C depends on several cofactors, which also have a negative affect on the rate of response to interferon-alpha-based therapy. Given the current worldwide prevalence of the metabolic syndrome, the impact of obesity and insulin resistance, and of their histopathological correlate, hepatic steatosis, on the natural history and management of chronic hepatitis C is undoubtedly very important. We will review some of the current knowledge on the clinical consequences of overweight/obesity, steatosis and insulin resistance on chronic hepatitis C, and discuss how this issue may be dealt with in clinical practice. IS - 10 JF - Journal of viral hepatitis SN - 1365-2893 EP - 688 TI - Impact of obesity, steatosis and insulin resistance on progression and response to therapy of hepatitis C. PB - Blackwell Publishing VL - 16 SP - 681 KW - hcv KW - irs KW - nash KW - obesity AU - Negro, F AU - Clément, S PY - 2009/10// UR - http://dx.doi.org/10.1111/j.1365-2893.2009.01186.x ER -