CDD: a database of conserved domain alignments with links to domain three-dimensional structure Export

@article{citeulike:912356, abstract = {The Conserved Domain Database (CDD) is a compilation of multiple sequence alignments representing protein domains conserved in molecular evolution. It has been populated with alignment data from the public collections Pfam and SMART, as well as with contributions from colleagues at NCBI. The current version of CDD (v.1.54) contains 3693 such models. CDD alignments are linked to protein sequence and structure data in Entrez. The molecular structure viewer Cn3D serves as a tool to interactively visualize alignments and three-dimensional structure, and to link three-dimensional residue coordinates to descriptions of evolutionary conservation. CDD can be accessed on the World Wide Web at http://www.ncbi.nlm.nih.gov/Structure/cdd/cdd.shtml. Protein query sequences may be compared against databases of position-specific score matrices derived from alignments in CDD, using a service named CD-Search, which can be found at http://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi. CD-Search runs reverse-position-specific BLAST (RPS-BLAST), a variant of the widely used PSI-BLAST algorithm. CD-Search is run by default for protein-protein queries submitted to NCBI's BLAST service at http://www.ncbi.nlm.nih.gov/BLAST. 10.1093/nar/30.1.281}, author = {Marchler-Bauer, Aron and Panchenko, Anna R. and Shoemaker, Benjamin A. and Thiessen, Paul A. and Geer, Lewis Y. and Bryant, Stephen H.}, citeulike-article-id = {912356}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/nar/30.1.281}, citeulike-linkout-1 = {http://nar.oxfordjournals.org/cgi/content/abstract/30/1/281}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/11752315}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=11752315}, day = {1}, doi = {10.1093/nar/30.1.281}, journal = {Nucl. Acids Res.}, keywords = {0cdd}, month = {January}, number = {1}, pages = {281--283}, posted-at = {2008-08-21 21:53:00}, priority = {2}, title = {CDD: a database of conserved domain alignments with links to domain three-dimensional structure}, url = {http://dx.doi.org/10.1093/nar/30.1.281}, volume = {30}, year = {2002} }

TY - JOUR ID - citeulike:912356 L3 - citeulike-article-id:912356 N2 - The Conserved Domain Database (CDD) is a compilation of multiple sequence alignments representing protein domains conserved in molecular evolution. It has been populated with alignment data from the public collections Pfam and SMART, as well as with contributions from colleagues at NCBI. The current version of CDD (v.1.54) contains 3693 such models. CDD alignments are linked to protein sequence and structure data in Entrez. The molecular structure viewer Cn3D serves as a tool to interactively visualize alignments and three-dimensional structure, and to link three-dimensional residue coordinates to descriptions of evolutionary conservation. CDD can be accessed on the World Wide Web at http://www.ncbi.nlm.nih.gov/Structure/cdd/cdd.shtml. Protein query sequences may be compared against databases of position-specific score matrices derived from alignments in CDD, using a service named CD-Search, which can be found at http://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi. CD-Search runs reverse-position-specific BLAST (RPS-BLAST), a variant of the widely used PSI-BLAST algorithm. CD-Search is run by default for protein-protein queries submitted to NCBI's BLAST service at http://www.ncbi.nlm.nih.gov/BLAST. 10.1093/nar/30.1.281 IS - 1 JF - Nucl. Acids Res. EP - 283 TI - CDD: a database of conserved domain alignments with links to domain three-dimensional structure VL - 30 SP - 281 KW - 0cdd AU - Marchler-Bauer, Aron AU - Panchenko, Anna AU - Shoemaker, Benjamin AU - Thiessen, Paul AU - Geer, Lewis AU - Bryant, Stephen PY - 2002/01/01/ UR - http://dx.doi.org/10.1093/nar/30.1.281 ER -