Human and other mammalian genomes contain transposons of the mariner family Export

@article{citeulike:6043735, abstract = {Internal fragments of the putative transposase gene of mariner -like elements (MLEs) were amplified from human, mouse, rat, chinese hamster, sheep and bovine genomic DNAs by polymerase chain reaction (PCR). The sequences identified in human, ovine and bovine genomes correspond to ancient degenerate transposons. Screening mammalian sequence libraries identified a truncated element in the human ABL gene and the sequence of its 5′-ITR was determined. This ITR sequences were used in PCR experiments with DNA from six mammalian species and detected full-sized and deleted MLEs. The presence of MLE in mammalian genomes demonstrates that they are ubiquitous mobile elements found from fungi to man. This observation strongly raises the possibility that MLE could constitute tools for the modification of eucaryotic genomes.}, author = {Augegouillou, C. and Bigot, Y. and Pollet, N. and Hamelin, M. and Meunierrotival, M. and Periquet, G.}, citeulike-article-id = {6043735}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/0014-5793(95)00735-R}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/001457939500735R}, day = {24}, doi = {10.1016/0014-5793(95)00735-R}, issn = {00145793}, journal = {FEBS Letters}, keywords = {genomes, human, mammalian, mariner}, month = {July}, number = {3}, pages = {541--546}, posted-at = {2009-10-30 17:36:45}, priority = {2}, title = {Human and other mammalian genomes contain transposons of the mariner family}, url = {http://dx.doi.org/10.1016/0014-5793(95)00735-R}, volume = {368}, year = {1995} }

TY - JOUR ID - citeulike:6043735 L3 - citeulike-article-id:6043735 N2 - Internal fragments of the putative transposase gene of mariner -like elements (MLEs) were amplified from human, mouse, rat, chinese hamster, sheep and bovine genomic DNAs by polymerase chain reaction (PCR). The sequences identified in human, ovine and bovine genomes correspond to ancient degenerate transposons. Screening mammalian sequence libraries identified a truncated element in the human ABL gene and the sequence of its 5′-ITR was determined. This ITR sequences were used in PCR experiments with DNA from six mammalian species and detected full-sized and deleted MLEs. The presence of MLE in mammalian genomes demonstrates that they are ubiquitous mobile elements found from fungi to man. This observation strongly raises the possibility that MLE could constitute tools for the modification of eucaryotic genomes. IS - 3 JF - FEBS Letters SN - 00145793 EP - 546 TI - Human and other mammalian genomes contain transposons of the mariner family VL - 368 SP - 541 KW - genomes KW - human KW - mammalian KW - mariner AU - Augegouillou, C AU - Bigot, Y AU - Pollet, N AU - Hamelin, M AU - Meunierrotival, M AU - Periquet, G PY - 1995/07/24/ UR - http://dx.doi.org/10.1016/0014-5793(95)00735-R ER -