AGE RELATED CHANGES AND INTERRELATIONSHIPS BETWEEN PLASMA TESTOSTERONE, OESTRADIOL AND TESTOSTERONE-BINDING GLOBULIN IN NORMAL ADULT MALES Export

@article{citeulike:5142793, abstract = {Testosterone (T), oestradiol-17{beta} (Oe2) and binding capacity of the testosterone-binding globulin (TeBG) were measured in plasma of 84 adult males (22-90 years). The medians for age group I (22- 61 years, n = 50) were: T 545 ng/100 ml, Oe2 1.66 ng/100 ml, TeBG capacity 1.44 {micro}g T/100 ml; the medians for age group II (67-90 years, n = 34) were: T 459 ng/100 ml, Oe2 2.56 ng/100 ml, TeBG capacity 2.05 {micro}g T/100 ml. The decrease of T and the increase of Oe2 and TeBG capacity with age were significant. The significant correlation (P < 0.01) for either age group between T and Oe2 may be ascribed to a simultaneous secretion and/or a peripheral conversion of T to Oe2. The significant correlation (P < 0.05) between T and TeBG for the old age group probably reflects the comparatively high percentage of total plasma T bound to TeBG. The biological meaning of the correlation between Oe2 and TeBG is discussed. 10.1530/acta.0.0740792}, author = {Pirke, Karl M. and Doerr, Peter}, citeulike-article-id = {5142793}, citeulike-linkout-0 = {http://dx.doi.org/10.1530/acta.0.0740792}, citeulike-linkout-1 = {http://www.eje-online.org/cgi/content/abstract/74/4/792}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/4800911}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=4800911}, day = {1}, doi = {10.1530/acta.0.0740792}, journal = {Acta Endocrinol}, keywords = {aging, anti-aging, endocrinology, estrogen, testosterone}, month = {December}, number = {4}, pages = {792--800}, posted-at = {2009-07-14 04:09:33}, priority = {2}, title = {AGE RELATED CHANGES AND INTERRELATIONSHIPS BETWEEN PLASMA TESTOSTERONE, OESTRADIOL AND TESTOSTERONE-BINDING GLOBULIN IN NORMAL ADULT MALES}, url = {http://dx.doi.org/10.1530/acta.0.0740792}, volume = {74}, year = {1973} }

TY - JOUR ID - citeulike:5142793 L3 - citeulike-article-id:5142793 N2 - Testosterone (T), oestradiol-17{beta} (Oe2) and binding capacity of the testosterone-binding globulin (TeBG) were measured in plasma of 84 adult males (22-90 years). The medians for age group I (22- 61 years, n = 50) were: T 545 ng/100 ml, Oe2 1.66 ng/100 ml, TeBG capacity 1.44 {micro}g T/100 ml; the medians for age group II (67-90 years, n = 34) were: T 459 ng/100 ml, Oe2 2.56 ng/100 ml, TeBG capacity 2.05 {micro}g T/100 ml. The decrease of T and the increase of Oe2 and TeBG capacity with age were significant. The significant correlation (P < 0.01) for either age group between T and Oe2 may be ascribed to a simultaneous secretion and/or a peripheral conversion of T to Oe2. The significant correlation (P < 0.05) between T and TeBG for the old age group probably reflects the comparatively high percentage of total plasma T bound to TeBG. The biological meaning of the correlation between Oe2 and TeBG is discussed. 10.1530/acta.0.0740792 IS - 4 JF - Acta Endocrinol EP - 800 TI - AGE RELATED CHANGES AND INTERRELATIONSHIPS BETWEEN PLASMA TESTOSTERONE, OESTRADIOL AND TESTOSTERONE-BINDING GLOBULIN IN NORMAL ADULT MALES VL - 74 SP - 792 KW - aging KW - anti-aging KW - endocrinology KW - estrogen KW - testosterone AU - Pirke, Karl AU - Doerr, Peter PY - 1973/12/01/ UR - http://dx.doi.org/10.1530/acta.0.0740792 ER -