Adaptation of orientation vectors of otolith-related central vestibular neurons to gravity. Export

@article{citeulike:4890272, abstract = {Behavioral experiments indicate that central pathways that process otolith-ocular and perceptual information have adaptive capabilities. Because polarization vectors of otolith afferents are directly related to the electro-mechanical properties of the hair cell bundle, it is unlikely that they change their direction of excitation. This indicates that the adaptation must take place in central pathways. Here we demonstrate for the first time that otolith polarization vectors of canal-otolith convergent neurons in the vestibular nuclei have adaptive capability. A total of 10 vestibular-only and vestibular-plus-saccade neurons were recorded extracellularly in two monkeys before and after they were in side-down positions for 2 h. The spatial characteristics of the otolith input were determined from the response vector orientation (RVO), which is the projection of the otolith polarization vector, onto the head horizontal plane. The RVOs had no specific orientation before animals were in side-down positions but moved toward the gravitational axis after the animals were tilted for extended periods. Vector reorientations varied from 0 to 109 degrees and were linearly related to the original deviation of the RVOs from gravity in the position of adaptation. Such reorientation of central polarization vectors could provide the basis for changes in perception and eye movements related to prolonged head tilts relative to gravity or in microgravity.}, author = {Eron, J. N. and Cohen, B. and Raphan, T. and Yakushin, S. B.}, citeulike-article-id = {4890272}, citeulike-linkout-0 = {http://dx.doi.org/10.1152/jn.90289.2008}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18497367}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18497367}, doi = {10.1152/jn.90289.2008}, issn = {0022-3077}, journal = {Journal of neurophysiology}, keywords = {adaptation, central, gravity, neuron, orientation, otolithc, vector, vestibular}, month = {September}, number = {3}, pages = {1686--1690}, posted-at = {2009-06-18 10:36:04}, priority = {2}, title = {Adaptation of orientation vectors of otolith-related central vestibular neurons to gravity.}, url = {http://dx.doi.org/10.1152/jn.90289.2008}, volume = {100}, year = {2008} }

TY - JOUR ID - citeulike:4890272 L3 - citeulike-article-id:4890272 N2 - Behavioral experiments indicate that central pathways that process otolith-ocular and perceptual information have adaptive capabilities. Because polarization vectors of otolith afferents are directly related to the electro-mechanical properties of the hair cell bundle, it is unlikely that they change their direction of excitation. This indicates that the adaptation must take place in central pathways. Here we demonstrate for the first time that otolith polarization vectors of canal-otolith convergent neurons in the vestibular nuclei have adaptive capability. A total of 10 vestibular-only and vestibular-plus-saccade neurons were recorded extracellularly in two monkeys before and after they were in side-down positions for 2 h. The spatial characteristics of the otolith input were determined from the response vector orientation (RVO), which is the projection of the otolith polarization vector, onto the head horizontal plane. The RVOs had no specific orientation before animals were in side-down positions but moved toward the gravitational axis after the animals were tilted for extended periods. Vector reorientations varied from 0 to 109 degrees and were linearly related to the original deviation of the RVOs from gravity in the position of adaptation. Such reorientation of central polarization vectors could provide the basis for changes in perception and eye movements related to prolonged head tilts relative to gravity or in microgravity. IS - 3 JF - Journal of neurophysiology SN - 0022-3077 EP - 1690 TI - Adaptation of orientation vectors of otolith-related central vestibular neurons to gravity. VL - 100 SP - 1686 KW - adaptation KW - central KW - gravity KW - neuron KW - orientation KW - otolithc KW - vector KW - vestibular AU - Eron, JN AU - Cohen, B AU - Raphan, T AU - Yakushin, SB PY - 2008/09// UR - http://dx.doi.org/10.1152/jn.90289.2008 ER -