higueruelo's 2009 [142 articles] Export

Recent papers added to higueruelo's library classified by the tag 2009. You can also see everyone's 2009.

	A novel and efficient tool for locating and characterizing protein cavities and binding sites [My Copy] Proteins: Structure, Function, and Bioinformatics, Vol. 9999, No. 9999. (11 September 2009), NA. by Ashutosh Tripathi, Glen E. Kellogg posted to shape ppi pocket interface 2009 by higueruelo on 2009-11-03 16:48:01 as along with 2 people nickolay ahmetbakan
	Identification of Lead Compounds As Antagonists of Protein Bcl-xL with a Diversity-Oriented Multidisciplinary Approach [My Copy] Journal of Medicinal Chemistry, Vol. 0, No. 0. (23 October 0000) by Simone Di Micco, Romina Vitale, Maurizio Pellecchia, et al.Michele F. Rega, Renata Riva, Andrea Basso, Giuseppe Bifulco posted to xf sm ppi dos bclxl 2009 by higueruelo on 2009-11-03 16:43:30 as along with 1 person jianfengcai
	Prediction of hot spot residues at protein-protein interfaces by combining machine learning and energy-based methods [My Copy] BMC Bioinformatics, Vol. 10, No. 1. (30 October 2009), 365. by Stefano Lise, Cedric Archambeau, Massimiliano Pontil, David Jones posted to ppi interface hotspots 2009 by higueruelo on 2009-11-03 16:40:16 as along with 6 people and 1 group sillitoe apaydin kshameer zwang phoenixzxl neils Orengo Group Journal Picks
	N-Acylpolyamine inhibitors of HDM2 and HDMX binding to p53. [My Copy] Bioorganic & medicinal chemistry (21 October 2009) by Ryo Hayashi, Deyun Wang, Toshiaki Hara, Jaclyn A. Iera, Stewart R. Durell, Daniel H. Appella posted to xf sm ppi p53 2009 by higueruelo on 2009-11-03 16:38:41 as
	Protein-protein interaction networks: how can a hub protein bind so many different partners? [My Copy] Trends in biochemical sciences (16 October 2009) by Chung-Jung J. Tsai, Buyong Ma, Ruth Nussinov posted to ppi hubs 2009 by higueruelo on 2009-11-03 16:29:59 as along with 1 person lymxz
	The role of dynamic conformational ensembles in biomolecular recognition [My Copy] Nature Chemical Biology, Vol. 5, No. 11. (10 October 2009), pp. 789-796. by David D. Boehr, Ruth Nussinov, Peter E. Wright posted to scissors flexibility 2009 by higueruelo on 2009-11-03 12:19:15 as along with 3 people skywalkerus02 ubcg08l paulschlesinger
	Physicochemical property profiles of marketed drugs, clinical candidates, and bioactive compounds [My Copy] Bioorganic & Medicinal Chemistry Letters (20 October 2009) by Christian Tyrchan, Niklas Blomberg, Ola Engkvist, Thierry Kogej, Sorel Muresan posted to scissors props druggable 2009 by higueruelo on 2009-10-23 14:49:05 as
	Atomic interactions and profile of small molecules disrupting protein-protein interfaces: the TIMBAL database. [My Copy] Chemical biology & drug design, Vol. 74, No. 5. (November 2009), pp. 457-467. by Alícia P. Higueruelo, Adrian Schreyer, G. Richard Bickerton, Will R. Pitt, Colin R. Groom, Tom L. Blundell posted to sm review ppi intimbal 2009 by higueruelo on 2009-10-14 14:35:53 as along with 1 person massivemayhem
	Investigation on the individual contributions of N--H...O==C and C--H...O==C interactions to the binding energies of beta-sheet models. [My Copy] Journal of computational chemistry (9 October 2009) by Chang-Sheng S. Wang, Chang-Liang L. Sun posted to thermo betaturn 2009 by higueruelo on 2009-10-14 14:33:33 as
	Steering Protein-Ligand Docking with Quantitative NMR Chemical Shift Perturbations. [My Copy] Journal of chemical information and modeling (2 October 2009) by Domingo González-Ruiz, Holger Gohlke posted to nmr docking 2009 by higueruelo on 2009-10-07 12:04:10 as
	A dynamic target-based pharmacophoric model mapping the CD4 binding site on HIV-1 gp120 to identify new inhibitors of gp120-CD4 protein-protein interactions. [My Copy] Bioorganic & medicinal chemistry letters (13 September 2009) by Fabiana Caporuscio, Andrea Tafi, Emmanuel González, Fabrizio Manetti, José A. Esté, Maurizio Botta posted to xf sm ppi hiv1 cd4 2009 by higueruelo on 2009-10-02 12:38:08 as
	The interwinding nature of protein-protein interfaces and its implication for protein complex formation [My Copy] Bioinformatics, Vol. 25, No. 23. (1 December 2009), pp. 3108-3113. by Kei Yura, Steven Hayward posted to ppi interface disorder 2009 by higueruelo on 2009-10-02 12:33:32 as along with 4 people kshameer dfdong tprpip phoenixzxl
	A Thermodynamic Approach to the Affinity Optimization of Drug Candidates [My Copy] Chemical Biology & Drug Design, Vol. 9999, No. 9999. (2009) by Ernesto Freire posted to thermo scissors 2009 by higueruelo on 2009-09-30 14:14:19 as
	Conformational Landscape of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Non-Nucleoside Inhibitor Binding Pocket: Lessons for Inhibitor Design from a Cluster Analysis of Many Crystal Structures [My Copy] Journal of Medicinal Chemistry, Vol. 0, No. 0. (0000) by Kristina A. Paris, Omar Haq, Anthony K. Felts, Kalyan Das, Eddy Arnold, Ronald M. Levy posted to hiv1 flexibility 2009 by higueruelo on 2009-09-26 12:40:52 as
	Intrinsically Disordered Proteins and Their Environment: Effects of Strong Denaturants, Temperature, pH, Counter Ions, Membranes, Binding Partners, Osmolytes, and Macromolecular Crowding. [My Copy] The protein journal (19 September 2009) by Vladimir N. Uversky posted to disorder 2009 by higueruelo on 2009-09-26 12:20:24 as
	Identification and Characterization of a Small Molecule Inhibitor of Fatty Acid Binding Proteins. [My Copy] Journal of medicinal chemistry (16 September 2009) by Ann V. Hertzel, Kristina Hellberg, Joseph M. Reynolds, et al.Andrew C. Kruse, Brittany E. Juhlmann, Anne J. Smith, Mark A. Sanders, Douglas H. Ohlendorf, Jill Suttles, David A. Bernlohr posted to xf sm ppi fattyacids 2009 by higueruelo on 2009-09-26 12:08:43 as
	Protein-Peptide Interactions Adopt the Same Structural Motifs as Monomeric Protein Folds [My Copy] Structure, Vol. 17, No. 8. (12 August 2009), pp. 1128-1136. by Peter Vanhee, Francois Stricher, Lies Baeten, et al.Erik Verschueren, Tom Lenaerts, Luis Serrano, Frederic Rousseau, Joost Schymkowitz posted to scissors ppi peptides folding 2009 by higueruelo on 2009-09-22 19:18:03 as
	Present and future challenges and limitations in protein-protein docking. [My Copy] Proteins (5 August 2009) by Carles Pons, Solène Grosdidier, Albert Solernou, Laura Pérez-Cano, Juan Fernández-Recio posted to ppi ppdocking 2009 by higueruelo on 2009-09-08 14:17:22 as
	Structural domain-domain interactions: Assessment and comparison with protein-protein interaction data to improve the interactome. [My Copy] Proteins, Vol. 9999, No. 9999. (5 August 2009), NA. by C. Prieto, J. De Las Rivas posted to ppi piccolo 2009 by higueruelo on 2009-09-08 14:16:32 as along with 2 people phoenixzxl zwang
	Influence of sequence changes and environment on intrinsically disordered proteins. [My Copy] PLoS computational biology, Vol. 5, No. 9. (4 September 2009), e1000497. by Amrita Mohan, Vladimir N. Uversky, Predrag Radivojac posted to disorder 2009 by higueruelo on 2009-09-08 14:08:26 as
	Knowledge-Based Virtual Screening: Application to the MDM4/p53 Protein-Protein Interaction. [My Copy] Methods in molecular biology (Clifton, N.J.), Vol. 575 (2009), pp. 173-194. by Edgar Jacoby, Andreas Boettcher, Lorenz M. Mayr, et al.Nathan Brown, Jeremy L. Jenkins, Joerg Kallen, Caroline Engeloch, Ulrich Schopfer, Pascal Furet, Keiichi Masuya, Joanna Lisztwan posted to xf vs sm ppi p53 mdm4 2009 by higueruelo on 2009-09-08 14:07:53 as
	Inhibition of a viral enzyme by a small-molecule dimer disruptor [My Copy] Nat Chem Biol, Vol. 5, No. 9. (September 2009), pp. 640-646. by Tina Shahian, Gregory M. Lee, Ana Lazic, et al.Leggy A. Arnold, Priya Velusamy, Christina M. Roels, R. Kiplin Guy, Charles S. Craik posted to xf sm ppi 2009 by higueruelo on 2009-09-04 11:17:19 as
	Protease dimer formation disrupted [My Copy] Nat Chem Biol, Vol. 5, No. 9. (September 2009), pp. 607-608. by Jean Chmielewski posted to xf sm ppi comment 2009 by higueruelo on 2009-09-04 11:13:52 as
	Assessing the druggability of protein-protein interactions by a supervised machine-learning method [My Copy] BMC Bioinformatics, Vol. 10, No. 1. (25 August 2009), 263. by Nobuyoshi Sugaya, Kazuyoshi Ikeda posted to xf sm ppi druggable 2009 by higueruelo on 2009-09-03 14:12:34 as along with 2 people iris_2001 phoenixzxl
	The origin of allosteric functional modulation: multiple pre-existing pathways. [My Copy] Structure (London, England : 1993), Vol. 17, No. 8. (12 August 2009), pp. 1042-1050. by Antonio del Sol, Chung-Jung J. Tsai, Buyong Ma, Ruth Nussinov posted to flexibility allosteric 2009 by higueruelo on 2009-09-03 14:10:36 as along with 4 people and 2 groups ubcg08l pablocarb okapi barry structural_bioinformatics McCammon
	Ligand efficiency and fragment-based drug discovery. [My Copy] Drug discovery today, Vol. 14, No. 5-6. (30 March 2009), pp. 278-283. by Scott D. Bembenek, Brett A. Tounge, Charles H. Reynolds posted to le fragments 2009 by higueruelo on 2009-08-12 14:07:47 as along with 3 people jerome sschurer pslee
	Computational fragment-based binding site identification by ligand competitive saturation. [My Copy] PLoS computational biology, Vol. 5, No. 7. (10 July 2009), e1000435. by Olgun Guvench, Alexander D. MacKerell posted to 2009 fragments interface pocket by higueruelo on 2009-08-10 16:28:39 as along with 5 people and 2 groups oteri NickFurnham TRHvidsten barry riffraff structural_bioinformatics McCammon
	From Fragment Screening to Potent Binders: Strategies for Fragment-to-Lead Evolution. [My Copy] Mini reviews in medicinal chemistry, Vol. 9, No. 8. (July 2009), pp. 956-961. by Krystian Eitner, Uwe Koch posted to 2009 frag2lead fragments by higueruelo on 2009-08-10 16:25:00 as
	Challenges of fragment screening [My Copy] Journal of Computer-Aided Molecular Design, Vol. 23, No. 8. (1 August 2009), pp. 449-451. by Diane Joseph-Mccarthy posted to 2009 fragments by higueruelo on 2009-08-10 16:13:14 as along with 3 people klexa ubcg08l jerome
	Computational design of affinity and specificity at protein–protein interfaces [My Copy] Current Opinion in Structural Biology, Vol. 19, No. 4. (29 August 2009), pp. 458-463. by John Karanicolas, Brian Kuhlman posted to 2009 computational interface ppi scissors thermo by higueruelo on 2009-08-10 14:33:09 as along with 4 people bmduggan sobolevnrm VGreiff barry
	Interaction between Intrinsically Disordered Proteins Frequently Occurs in a Human Protein–Protein Interaction Network [My Copy] Journal of Molecular Biology, Vol. 392, No. 5. (09 October 2009), pp. 1253-1265. by Kana Shimizu, Hiroyuki Toh posted to 2009 disorder ppi by higueruelo on 2009-08-10 14:18:21 as along with 8 people and 1 group jjray bdessailly nzm ekotelnikova kiekyon tprpip cabbagesofdoom reyez Orengo Group Journal Picks
	Quantitative analysis of caspase-3 activation by fitting fluorescence emission spectra in living cells. [My Copy] Micron (Oxford, England : 1993) (23 July 2009) by Longxiang Wang, Tongsheng Chen, Junle Qu, Xunbin Wei posted to 2009 assays ppi by higueruelo on 2009-08-10 14:15:28 as
	Studying the salt dependence of the binding of sigma70 and sigma32 to core RNA polymerase using luminescence resonance energy transfer. [My Copy] PloS one, Vol. 4, No. 8. (2009) by Bryan T. Glaser, Veit Bergendahl, Larry C. Anthony, Brian Olson, Richard R. Burgess posted to 2009 assays ppi by higueruelo on 2009-08-10 14:14:56 as
	Structural and Biophysical Characterization of XIAP BIR3 G306E Mutant: Insights in Protein Dynamics and Application for Fragment-Based Drug Design. [My Copy] Chemical biology & drug design (29 July 2009) by Cathy D. Moore, Haihong Wu, Ben Bolanños, et al.Simon Bergqvist, Alexei Brooun, Tom Pauly, Dawn Nowlin posted to 2009 flexibility fragments mutant-design ppi sm xf by higueruelo on 2009-08-10 14:12:39 as
	Structural interactomics: informatics approaches to aid the interpretation of genetic variation and the development of novel therapeutics [My Copy] Mol. BioSyst. (2009) by Semin Lee, Alan Brown, William R. Pitt, et al.Alicia P. Higueruelo, Sungsam Gong, George R. Bickerton, Adrian Schreyer, Duangrudee Tanramluk, Alison Baylay, Tom L. Blundell posted to 2009 review systemsbio by higueruelo on 2009-08-07 15:31:34 as along with 1 person ubcg08l
	The isolation, total synthesis and structure elucidation of chlorofusin, a natural product inhibitor of the p53-mDM2 protein-protein interaction. [My Copy] Natural product reports, Vol. 26, No. 4. (April 2009), pp. 465-477. by Ryan C. Clark, Sang Yeul Y. Lee, Mark Searcey, Dale L. Boger posted to 2009 mdm2 np p53 ppi xf by higueruelo on 2009-08-03 15:57:31 as
	Novel In Vitro Protein Fragment Complementation Assay Applicable to High-Throughput Screening in a 1536-Well Format. [My Copy] Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening (29 July 2009) by Junko Hashimoto, Taku Watanabe, Tatsuya Seki, et al.Satoshi Karasawa, Miho Izumikawa, Tomoe Seki, Shun-Ichiro I. Iemura, Tohru Natsume, Nobuo Nomura, Naoki Goshima, Atsushi Miyawaki, Motoki Takagi, Kazuo Shin-Ya posted to 2009 assays pac1 pac3 ppi sm xf by higueruelo on 2009-08-03 15:56:24 as
	In silico-in vitro screening of protein-protein interactions: towards the next generation of therapeutics. [My Copy] Current pharmaceutical biotechnology, Vol. 9, No. 2. (April 2008), pp. 103-122. by B. O. Villoutreix, K. Bastard, O. Sperandio, et al.R. Fahraeus, J. L. Poyet, F. Calvo, B. Déprez, M. A. Miteva posted to 2009 computational druggable interface ppi sm by higueruelo on 2009-07-29 14:54:32 as along with 1 person flbarroso
	Small Molecule Chloropyramine Hydrochloride (C4) Targets the Binding Site of Focal Adhesion Kinase and Vascular Endothelial Growth Factor Receptor 3 and Suppresses Breast Cancer Growth in Vivo [My Copy] Journal of Medicinal Chemistry, Vol. 0, No. 0. (0000) by Elena V. Kurenova, Darell L. Hunt, Dihua He, Andrew T. Magis, David A. Ostrov, William G. Cance posted to 2009 bromodomain fak ppi sm vegfr-3 xf by higueruelo on 2009-07-29 14:50:09 as
	Energy based approach for understanding the recognition mechanism in protein-protein complexes. [My Copy] Molecular bioSystems (7 July 2009) by Michael M. Gromiha, Kiyonobu Yokota, Kazuhiko Fukui posted to 2009 hotspots interface ppi by higueruelo on 2009-07-29 14:44:53 as
	Modulating proteostasis: peptidomimetic inhibitors and activators of protein folding. [My Copy] Current pharmaceutical design, Vol. 15, No. 21. (2009), pp. 2488-2507. by F. Hatahet, L. W. Ruddock posted to 2009 folding peptidomimetics by higueruelo on 2009-07-29 14:42:13 as
	Predicting intrinsic disorder in proteins: an overview [My Copy] Cell Research, Vol. 19, No. 8. (01 August 2009), pp. 929-949. by Bo He, Kejun Wang, Yunlong Liu, Bin Xue, Vladimir N. Uversky, A. Keith Dunker posted to 2009 disorder review by higueruelo on 2009-07-29 14:35:11 as
	Protein disorder in the human diseasome: unfoldomics of human genetic diseases. [My Copy] BMC genomics, Vol. 10 Suppl 1 (2009) by U. Midic, C. J. Oldfield, A. K. Dunker, Z. Obradovic, V. N. Uversky posted to 2009 disorder druggable by higueruelo on 2009-07-29 14:34:35 as
	Unfoldomics of human diseases: linking protein intrinsic disorder with diseases [My Copy] BMC Genomics, Vol. 10, No. Suppl 1. (2009), S7. by Vladimir Uversky, Christopher Oldfield, Uros Midic, et al.Hongbo Xie, Bin Xue, Slobodan Vucetic, Lilia Iakoucheva, Zoran Obradovic, A. Keith Dunker posted to 2009 disorder druggable by higueruelo on 2009-07-29 14:33:47 as along with 1 person kiekyon
	Hierarchical plasticity from pair distance fluctuations [My Copy] Physical Biology, Vol. 6, No. 3. (September 2009), 036017. by S. A. Menor, Adam M. Graff, M. F. Thorpe posted to 2009 complex flexibility ppi by higueruelo on 2009-07-29 14:32:48 as along with 1 person sobolevnrm
	Targeting rho GTPases by peptidic structures. [My Copy] Current pharmaceutical design, Vol. 15, No. 21. (2009), pp. 2481-2487. by F. Marchioni, Y. Zheng posted to 2009 gtpases peptidomimetics ppi rho by higueruelo on 2009-07-29 14:29:07 as
	Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography (dagger). [My Copy] Journal of medicinal chemistry, Vol. 0, No. 0. (20 July 2009) by Douglas R. Davies, Bjorn Mamat, Olafur T. Magnusson, et al.Jeff Christensen, Magnus H. Haraldsson, Rama Mishra, Brian Pease, Erik Hansen, Jasbir Singh, David Zembower, Hidong Kim, Alex S. Kiselyov, Alex B. Burgin, Mark E. Gurney, Lance J. Stewart posted to 2009 fragments by higueruelo on 2009-07-29 14:27:33 as
	Organic dyes as small molecule protein-protein interaction inhibitors for the CD40-CD154 costimulatory interaction. [My Copy] Journal of molecular recognition : JMR (20 July 2009) by Peter Buchwald, Emilio Margolles-Clark, Norma S. Kenyon, Camillo Ricordi posted to 2009 cd154 cd40 ppi xf xm by higueruelo on 2009-07-29 14:24:26 as
	Probing hot spots on protein-protein interfaces with all-atom free-energy simulation. [My Copy] The Journal of chemical physics, Vol. 131, No. 3. (21 July 2009) by I. Meliciani, K. Klenin, T. Strunk, K. Schmitz, W. Wenzel posted to 2009 alascanning computational hotspots ppi by higueruelo on 2009-07-29 14:02:51 as
	Linking folding and binding [My Copy] Current Opinion in Structural Biology, Vol. 19, No. 1. (February 2009), pp. 31-38. by Peter E. Wright, H. Jane Dyson posted to 2009 disorder folding review thermo by higueruelo on 2009-07-28 12:15:55 as along with 3 people and 1 group chemrahul82 sobolevnrm flbarroso baker-group

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ppi	438
xf	262
sm	241
review	165
2008	164
2007	144
2009	142
flexibility	84
interface	78
2005	58
2006	57
peptidomimetics	51
disorder	41
intimbal	41
2004	35
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thermo	33
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dynamics	24
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higueruelo's 2009 [142 articles] Export

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