higueruelo's p53 [26 articles] Export

Recent papers added to higueruelo's library classified by the tag p53. You can also see everyone's p53.

	N-Acylpolyamine inhibitors of HDM2 and HDMX binding to p53. [My Copy] Bioorganic & medicinal chemistry (21 October 2009) by Ryo Hayashi, Deyun Wang, Toshiaki Hara, Jaclyn A. Iera, Stewart R. Durell, Daniel H. Appella posted to xf sm ppi p53 2009 by higueruelo on 2009-11-03 16:38:41 as
	Knowledge-Based Virtual Screening: Application to the MDM4/p53 Protein-Protein Interaction. [My Copy] Methods in molecular biology (Clifton, N.J.), Vol. 575 (2009), pp. 173-194. by Edgar Jacoby, Andreas Boettcher, Lorenz M. Mayr, et al.Nathan Brown, Jeremy L. Jenkins, Joerg Kallen, Caroline Engeloch, Ulrich Schopfer, Pascal Furet, Keiichi Masuya, Joanna Lisztwan posted to xf vs sm ppi p53 mdm4 2009 by higueruelo on 2009-09-08 14:07:53 as
	The isolation, total synthesis and structure elucidation of chlorofusin, a natural product inhibitor of the p53-mDM2 protein-protein interaction. [My Copy] Natural product reports, Vol. 26, No. 4. (April 2009), pp. 465-477. by Ryan C. Clark, Sang Yeul Y. Lee, Mark Searcey, Dale L. Boger posted to 2009 mdm2 np p53 ppi xf by higueruelo on 2009-08-03 15:57:31 as
	Small Molecules Bound to Unique Sites in the Target Protein Binding Cleft of Calcium-Bound S100B As Characterized by Nuclear Magnetic Resonance and X-ray Crystallography [My Copy] Biochemistry, Vol. 48, No. 26. (7 July 2009), pp. 6202-6212. by Thomas H. Charpentier, Paul T. Wilder, Melissa A. Liriano, et al.Kristen M. Varney, Shijun Zhong, Andrew Coop, Edwin Pozharski, Alexander D. Mackerell, Eric A. Toth, David J. Weber posted to 2009 flexibility p53 ppi s100b sm xf by higueruelo on 2009-06-03 10:12:35 as along with 1 person carlosjavierna
	Study of MDM2 Binding to p53-Analogues: Affinity, Helicity, and Applicability to Drug Design. [My Copy] Journal of chemical information and modeling (26 March 2009) by Ori Kalid, Nir Ben-Tal posted to 2009 flexibility mdm2 p53 peptidomimetics ppi by higueruelo on 2009-04-01 08:49:27 as
	Small-molecule inhibitors of the p53-HDM2 interaction for the treatment of cancer. [My Copy] Expert opinion on investigational drugs, Vol. 17, No. 12. (December 2008), pp. 1865-1882. by S. Patel, M. R. Player posted to 2008 mdm2 p53 ppi review sm xf by higueruelo on 2008-11-19 13:36:03 as
	Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy. [My Copy] Annual review of pharmacology and toxicology (3 October 2008) by Sanjeev Shangary, Shaomeng Wang posted to 2008 mdm2 p53 ppi review sm xf by higueruelo on 2008-10-07 23:36:18 as along with 1 person guhjy
	Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners. [My Copy] BMC genomics, Vol. 9 Suppl 1 (2008) by C. J. Oldfield, J. Meng, J. Y. Yang, M. Q. Yang, V. N. Uversky, A. K. Dunker posted to 2008 disorder hubs p53 by higueruelo on 2008-09-12 15:23:57 as along with 2 people carlosjavierna Evangelia
	Small Molecule Inhibitors of the p53-MDM2. [My Copy] Current medicinal chemistry, Vol. 15, No. 17. (2008), pp. 1720-1730. by C. Q. Hu, Y. Z. Hu posted to 2008 mdm2 p53 ppi review sm xf by higueruelo on 2008-09-10 16:16:22 as
	Small molecules targeting p53 to improve antitumor therapy. [My Copy] Mini reviews in medicinal chemistry, Vol. 8, No. 9. (August 2008), pp. 856-868. by G. L. Beretta, L. Gatti, V. Benedetti, P. Perego, F. Zunino posted to 2008 p53 ppi review sm xf by higueruelo on 2008-09-05 12:20:01 as
	Targeting the MDM2-p53 Interaction for Cancer Therapy. [My Copy] Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, No. 17. (1 September 2008), pp. 5318-5324. by S. Shangary, S. Wang posted to 2008 mdm2 p53 ppi review sm xf by higueruelo on 2008-09-04 16:18:00 as along with 1 person guhjy
	Small molecular weight protein-protein interaction antagonists--an insurmountable challenge? [My Copy] Current Opinion in Chemical Biology, Vol. 12, No. 3. (June 2008), pp. 281-291. by Alexander Dömling posted to 2008 mdm2 p53 ppi sm xf by higueruelo on 2008-07-17 10:06:39 as
	Computational studies and peptidomimetic design for the human p53-MDM2 complex. [My Copy] Proteins, Vol. 58, No. 1. (1 January 2005), pp. 222-234. by H. Zhong, H. A. Carlson posted to 2005 mdm2 p53 peptidomimetics ppi by higueruelo on 2008-07-07 11:52:28 as along with 1 person blackbart
	Using a beta-hairpin to mimic an alpha-helix: cyclic peptidomimetic inhibitors of the p53-HDM2 protein-protein interaction. [My Copy] Angewandte Chemie (International ed. in English), Vol. 43, No. 16. (13 April 2004), pp. 2109-2112. by R. Fasan, R. L. Dias, K. Moehle, et al.O. Zerbe, J. W. Vrijbloed, D. Obrecht, J. A. Robinson posted to 2004 betaturn mdm2 p53 peptidomimetics sm xf by higueruelo on 2008-07-01 16:50:05 as
	Quantitative lid dynamics of MDM2 reveals differential ligand binding modes of the p53-binding cleft. [My Copy] Journal of the American Chemical Society, Vol. 130, No. 20. (21 May 2008), pp. 6472-6478. by S. A. Showalter, L. Bruschweiler-Li, E. Johnson, F. Zhang, R. Brüschweiler posted to 2008 complex dynamics flexibility mdm2 p53 ppi sm by higueruelo on 2008-06-24 19:48:58 as
	A facile method to screen inhibitors of protein-protein interactions including MDM2-p53 displayed on T7 phage. [My Copy] Biochemical pharmacology, Vol. 75, No. 9. (1 May 2008), pp. 1743-1750. by K. Ishi, F. Sugawara posted to 2008 mdm2 p53 phage ppi sm xf by higueruelo on 2008-04-22 10:33:08 as
	Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy. [My Copy] J Med Chem, Vol. 49, No. 13. (29 June 2006), pp. 3759-3762. by Y. Lu, Z. Nikolovska-Coleska, X. Fang, et al.W. Gao, S. Shangary, S. Qiu, D. Qin, S. Wang posted to 2006 mdm2 p53 ppi sm xf by higueruelo on 2008-01-28 12:00:04 as along with 2 people blackbart pkolb
	Development of E3-substrate (MDM2-p53)-binding inhibitors: structural aspects. [My Copy] Methods Enzymol, Vol. 399 (2005), pp. 622-633. by D. C. Fry, B. Graves, L. T. Vassilev posted to 2005 mdm2 p53 ppi review sm xf by higueruelo on 2007-12-01 19:57:59 as
	Small Molecule Protein-Protein Inhibitors for the p53-MDM2 Interaction [My Copy] pp. 952-960. by Anna S. Dudkina, Craig W. Lindsley posted to 2007 ctmc7 mdm2 p53 ppi review sm xf by higueruelo on 2007-12-01 17:25:42 as
	Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction. [My Copy] J Med Chem, Vol. 49, No. 12. (15 June 2006), pp. 3432-3435. by K. Ding, Y. Lu, Z. Nikolovska-Coleska, et al.G. Wang, S. Qiu, S. Shangary, W. Gao, D. Qin, J. Stuckey, K. Krajewski, P. P. Roller, S. Wang posted to 2006 mdm2 p53 ppi sm xf by higueruelo on 2007-12-01 15:15:05 as along with 1 person blackbart
	NMR structure of a complex between MDM2 and a small molecule inhibitor [My Copy] Journal of Biomolecular NMR, Vol. 30, No. 2., 163. by David C. Fry, S. Donald Emerson, Stefan Palme, Binh T. Vu, Chao-Min Liu, Frank Podlaski posted to 2004 mdm2 nmr p53 ppi roche sm xf by higueruelo on 2007-12-01 15:13:11 as
	Small Molecule Inhibitors of the MDM2-p53 Interaction Discovered by Ensemble-Based Receptor Models [My Copy] J. Am. Chem. Soc., Vol. 129, No. 42. (24 October 2007), pp. 12809-12814. by A. L. Bowman, Z. Nikolovska-Coleska, H. Zhong, S. Wang, H. A. Carlson posted to 2007 flexibility mdm2 p53 ppi sm vs xf by higueruelo on 2007-12-01 15:07:18 as
	The p53–Mdm2–HAUSP complex is involved in p53 stabilization by HAUSP [My Copy] Oncogene, Vol. aop, No. current. by C. L. Brooks, M. Li, M. Hu, Y. Shi, W. Gu posted to 2007 complex hausp mdm2 p53 ppi by higueruelo on 2007-12-01 15:02:41 as along with 1 person Dualsystems
	Identification and Characterization of Small Molecule Inhibitors of the Calcium-Dependent S100B-p53 Tumor Suppressor Interaction [My Copy] J. Med. Chem., Vol. 47, No. 21. (7 October 2004), pp. 5085-5093. by J. Markowitz, I. Chen, R. Gitti, et al.D. M. Baldisseri, Y. Pan, R. Udan, F. Carrier, A. D. Mackerell, D. J. Weber posted to 2004 intimbal p53 ppi s100b sm by higueruelo on 2007-11-26 17:18:40 as
	Peptide, Peptidomimetic, and Small-molecule Antagonists of the p53HDM2 ProteinProtein Interaction [My Copy] International Journal of Peptide Research and Therapeutics, Vol. 12, No. 1. (March 2006), pp. 3-19. by Peter M. Fischer posted to 2006 intimbal mdm2 p53 peptidomimetics ppi review sm by higueruelo on 2007-11-26 17:02:12 as
	Targeting protein-protein interactions: Lessons from p53/MDM2. [My Copy] Biopolymers, Vol. 88, No. 5. (10 April 2007), pp. 657-686. by Justin K K. Murray, Samuel H H. Gellman posted to 2007 intimbal mdm2 p53 ppi review sm by higueruelo on 2007-11-26 16:48:04 as along with 2 people guhjy yeastyboy

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ppi	441
xf	263
sm	242
review	166
2008	164
2009	145
2007	144
flexibility	84
interface	78
2005	58
2006	57
peptidomimetics	51
disorder	41
intimbal	41
2004	35
druggable	34
thermo	33
allosteric	32
sm-prot	27
db	27
p53	26
hotspots	25
peptides	25
dynamics	24
pocket	24
mdm2	22
struct-determination	21
fragments	21
bcl2	21
2002	20
complex	20
hiv1	19
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2003	17
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higueruelo's p53 [26 articles] Export

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