Knee cartilage injury after tibial lengthening:Radiographic and histological studies in rabbits after 3-6 months

@article{citeulike:3574222, abstract = {We investigated the effects of tibial lengthening by callotasis on the knee articular cartilage in 10 rabbits at 3 and 6 months after distraction. The distraction rate was 1 mm per day, until a 30 percent gain in length. On the right tibia, the daily distraction frequency was in 2 steps by hand, while on the left it was in 120 steps by an autodistractor. 5 animals were killed at 3 months and 5 at 6 months following distraction, and their knee joints were radiographically and histologically examined. On the 2-step side, arthrotic changes at 3 and 6 months after distraction were found in 3 of 5 and 4 of 5 knees, respectively. The severity of change increased with time. On the 120-step side, however, no arthrotic changes were found, except in one knee at 6 months. Our findings suggest that by increasing the frequency of distraction for limb lengthening one can prevent the onset of arthrosis in adjacent joints.}, author = {Nakamura, Eiichi and Mizuta, Hiroshi and Takagi, Katsumasa}, citeulike-article-id = {3574222}, doi = {10.3109/17453679508995551}, journal = {Acta Orthopaedica}, keywords = {cartilage, distraction, dog, experimental, femur, joint, lengthening}, number = {4}, pages = {313--316}, posted-at = {2008-11-18 12:56:53}, priority = {2}, publisher = {Informa Healthcare}, title = {Knee cartilage injury after tibial lengthening:Radiographic and histological studies in rabbits after 3-6 months}, url = {http://dx.doi.org/10.3109/17453679508995551}, volume = {66}, year = {1995} }

TY - JOUR ID - citeulike:3574222 L3 - citeulike-article-id:3574222 N2 - We investigated the effects of tibial lengthening by callotasis on the knee articular cartilage in 10 rabbits at 3 and 6 months after distraction. The distraction rate was 1 mm per day, until a 30 percent gain in length. On the right tibia, the daily distraction frequency was in 2 steps by hand, while on the left it was in 120 steps by an autodistractor. 5 animals were killed at 3 months and 5 at 6 months following distraction, and their knee joints were radiographically and histologically examined. On the 2-step side, arthrotic changes at 3 and 6 months after distraction were found in 3 of 5 and 4 of 5 knees, respectively. The severity of change increased with time. On the 120-step side, however, no arthrotic changes were found, except in one knee at 6 months. Our findings suggest that by increasing the frequency of distraction for limb lengthening one can prevent the onset of arthrosis in adjacent joints. IS - 4 JF - Acta Orthopaedica EP - 316 TI - Knee cartilage injury after tibial lengthening:Radiographic and histological studies in rabbits after 3-6 months PB - Informa Healthcare VL - 66 SP - 313 KW - cartilage KW - distraction KW - dog KW - experimental KW - femur KW - joint KW - lengthening AU - Nakamura, Eiichi AU - Mizuta, Hiroshi AU - Takagi, Katsumasa PY - 1995/// UR - http://dx.doi.org/10.3109/17453679508995551 ER -