Ammonia pulses and metabolic oscillations guide yeast colony development. Export

@article{citeulike:2842914, abstract = {On solid substrate, growing yeast colonies alternately acidify and alkalinize the medium. Using morphological, cytochemical, genetic, and DNA microarray approaches, we characterized six temporal steps in the "acid-to-alkali" colony transition. This transition is connected with the production of volatile ammonia acting as starvation signal between colonies. We present evidence that the three membrane proteins Ato1p, Ato2p, and Ato3p, members of the YaaH family, are involved in ammonia production in Saccharomyces cerevisiae colonies. The acid-to-alkali transition is connected with decrease of mitochondrial oxidative catabolism and by peroxisome activation, which in parallel with activation of biosynthetic pathways contribute to decrease the general stress level in colonies. These metabolic features characterize a novel survival strategy used by yeast under starvation conditions prevalent in nature.}, author = {Palkov\'{a}, Zdena and Devaux, Fr\'{e}d\'{e}ric and Icicov\'{a}, Mark\'{e}ta and Min\'{a}rikov\'{a}, Lucie and Le Crom, St\'{e}phane and Jacq, Claude}, citeulike-article-id = {2842914}, citeulike-linkout-0 = {http://dx.doi.org/10.1091/mbc.E01-12-0149}, citeulike-linkout-1 = {http://www.molbiolcell.org/cgi/content/abstract/13/11/3901}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/12429834}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=12429834}, day = {1}, doi = {10.1091/mbc.E01-12-0149}, issn = {1059-1524}, journal = {Molecular biology of the cell}, keywords = {acs1}, month = {November}, number = {11}, pages = {3901--3914}, posted-at = {2008-05-29 00:43:39}, priority = {2}, title = {Ammonia pulses and metabolic oscillations guide yeast colony development.}, url = {http://dx.doi.org/10.1091/mbc.E01-12-0149}, volume = {13}, year = {2002} }

TY - JOUR ID - citeulike:2842914 L3 - citeulike-article-id:2842914 N2 - On solid substrate, growing yeast colonies alternately acidify and alkalinize the medium. Using morphological, cytochemical, genetic, and DNA microarray approaches, we characterized six temporal steps in the "acid-to-alkali" colony transition. This transition is connected with the production of volatile ammonia acting as starvation signal between colonies. We present evidence that the three membrane proteins Ato1p, Ato2p, and Ato3p, members of the YaaH family, are involved in ammonia production in Saccharomyces cerevisiae colonies. The acid-to-alkali transition is connected with decrease of mitochondrial oxidative catabolism and by peroxisome activation, which in parallel with activation of biosynthetic pathways contribute to decrease the general stress level in colonies. These metabolic features characterize a novel survival strategy used by yeast under starvation conditions prevalent in nature. IS - 11 JF - Molecular biology of the cell SN - 1059-1524 EP - 3914 TI - Ammonia pulses and metabolic oscillations guide yeast colony development. VL - 13 SP - 3901 KW - acs1 AU - Palková, Zdena AU - Devaux, Frédéric AU - Icicová, Markéta AU - Mináriková, Lucie AU - Le Crom, Stéphane AU - Jacq, Claude PY - 2002/11/01/ UR - http://dx.doi.org/10.1091/mbc.E01-12-0149 ER -