After a survey of the present state of cosmological theory and observations, this article discusses a series of major themes underlying the relation of philosophy to cosmology. These are: A: The uniqueness of the universe; B: The large scale of the universe in space and time; C: The unbound energies in the early universe; D: Explaining the universe -- the question of origins; E: The universe as the background for existence; F: The explicit philosophical basis; G: The Anthropic question: fine tuning for life; H: The possible existence of multiverses; I: The natures of existence. Each of these themes is explored and related to a series of Theses that set out the major issues confronting cosmology in relation to philosophy.