On the biogenesis of myelin membranes: Sorting, trafficking and cell polarity. Export

@article{citeulike:6097965, abstract = {In the central nervous system, a multilayered membrane layer known as the myelin sheath enwraps axons, and is required for optimal saltatory signal conductance. The sheath develops from membrane processes that extend from the plasma membrane of oligodendrocytes and displays a unique lipid and protein composition. Myelin biogenesis is carefully regulated, and multiple transport pathways involving a variety of endosomal compartments are involved. Here we briefly summarize how the major myelin proteins proteolipid protein and myelin basic protein reach the sheath, and highlight potential mechanisms involved, including the role of myelin specific lipids and cell polarity related transport pathways.}, author = {Baron, Wia and Hoekstra, Dick}, citeulike-article-id = {6097965}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.febslet.2009.10.085}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/19896485}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=19896485}, day = {6}, doi = {10.1016/j.febslet.2009.10.085}, issn = {1873-3468}, journal = {FEBS letters}, keywords = {myelin, sorting, tesis, trafficking}, month = {November}, posted-at = {2009-11-11 12:14:29}, priority = {2}, title = {On the biogenesis of myelin membranes: Sorting, trafficking and cell polarity.}, url = {http://dx.doi.org/10.1016/j.febslet.2009.10.085}, year = {2009} }

TY - JOUR ID - citeulike:6097965 L3 - citeulike-article-id:6097965 N2 - In the central nervous system, a multilayered membrane layer known as the myelin sheath enwraps axons, and is required for optimal saltatory signal conductance. The sheath develops from membrane processes that extend from the plasma membrane of oligodendrocytes and displays a unique lipid and protein composition. Myelin biogenesis is carefully regulated, and multiple transport pathways involving a variety of endosomal compartments are involved. Here we briefly summarize how the major myelin proteins proteolipid protein and myelin basic protein reach the sheath, and highlight potential mechanisms involved, including the role of myelin specific lipids and cell polarity related transport pathways. JF - FEBS letters SN - 1873-3468 TI - On the biogenesis of myelin membranes: Sorting, trafficking and cell polarity. KW - myelin KW - sorting KW - tesis KW - trafficking AU - Baron, Wia AU - Hoekstra, Dick PY - 2009/11/06/ UR - http://dx.doi.org/10.1016/j.febslet.2009.10.085 ER -