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	Phosphorylated high molecular weight neurofilament protein in lower motor neurons in amyotrophic lateral sclerosis and other neurodegenerative diseases involving ventral horn cells. [My Copy] Acta neuropathologica, Vol. 79, No. 4. (1990), pp. 402-408. by G. Sobue, Y. Hashizume, T. Yasuda, et al.E. Mukai, T. Kumagai, T. Mitsuma, J. Q. Trojanowski posted to aggregation als histopathology mnd motoneuron neurofilament sbma by inbetweener on 2009-06-29 23:37:53 as
	Motoneuronal cell death is not correlated with aggregate formation of androgen receptors containing an elongated polyglutamine tract. [My Copy] Human molecular genetics, Vol. 9, No. 1. (1 January 2000), pp. 133-144. by S. Simeoni, M. A. Mancini, D. L. Stenoien, et al.M. Marcelli, N. L. Weigel, M. Zanisi, L. Martini, A. Poletti posted to aggregation ar axonaltransport motoneuron sbma by inbetweener on 2009-06-28 00:03:55 as
	ESCRT-III Dysfunction Causes Autophagosome Accumulation and Neurodegeneration [My Copy] Current Biology, Vol. In Press, Corrected Proof by Jin-A Lee, Anne Beigneux, Tariq S. Ahmad, Stephen G. Young, Fen-Biao Gao posted to aggregation autophagy endosome inclusions neurodegeneration by inbetweener on 2009-05-27 20:34:26 as along with 1 person and 1 group andygrierson Sheffield_Neuroscience
	Chaperone suppression of cellular toxicity of huntingtin is independent of polyglutamine aggregation. [My Copy] The Journal of biological chemistry, Vol. 276, No. 51. (21 December 2001), pp. 48417-48424. by H. Zhou, S. H. Li, X. J. Li posted to aggregation chaperone heatshock by inbetweener on 2009-05-18 19:04:41 as
	Archaeal proteasomes effectively degrade aggregation-prone proteins and reduce cellular toxicities in mammalian cells. [My Copy] J Biol Chem (22 June 2006) by Shin-Ichi I. Yamada, Jun-Ichi I. Niwa, Shinsuke Ishigaki, et al.Miho Takahashi, Takashi Ito, Jun Sone, Manabu Doyu, Gen Sobue posted to aggregation als ar cell proteasome proteindegradation sod1 by inbetweener on 2009-05-17 18:26:37 as along with 1 person leemary4
	Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei. [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, No. 13. (22 June 1999), pp. 7388-7393. by M. V. Karpuj, H. Garren, H. Slunt, et al.D. L. Price, J. Gusella, M. W. Becher, L. Steinman posted to aggregation hd polyglutamine transglutaminase by inbetweener on 2009-05-07 10:42:24 as
	Disease-associated mutant ubiquitin causes proteasomal impairment and enhances the toxicity of protein aggregates. [My Copy] PLoS genetics, Vol. 5, No. 2. (February 2009) by E. M. Tank, H. L. True posted to aggregation geneticdisease ups by inbetweener on 2009-04-21 19:51:44 as
	Acetylation targets mutant huntingtin to autophagosomes for degradation. [My Copy] Cell, Vol. 137, No. 1. (3 April 2009), pp. 60-72. by H. Jeong, F. Then, T. J. Melia, et al.J. R. Mazzulli, L. Cui, J. N. Savas, C. Voisine, P. Paganetti, N. Tanese, A. C. Hart, A. Yamamoto, D. Krainc posted to aggregation autophagy hd by inbetweener on 2009-04-14 19:18:53 as
	Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions. [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, No. 32. (9 August 2005), pp. 11402-11407. by E. J. Slow, R. K. Graham, A. P. Osmand, et al.R. S. Devon, G. Lu, Y. Deng, J. Pearson, K. Vaid, N. Bissada, R. Wetzel, B. R. Leavitt, M. R. Hayden posted to aggregation hd huntingtin inclusions model mouse neurodegeneration by inbetweener on 2008-12-09 17:54:52 as
	Huntingtons disease: degradation of mutant huntingtin by autophagy [My Copy] FEBS Journal, Vol. 275, No. 17. (September 2008), pp. 4263-4270. by Sarkar, Sovan, Rubinsztein, C. David posted to aggregation autophagy hd proteindegradation review by inbetweener on 2008-12-09 17:19:51 as
	Huntingtin Expression Stimulates Endosomal-Lysosomal Activity, Endosome Tubulation, and Autophagy [My Copy] J. Neurosci., Vol. 20, No. 19. (1 October 2000), pp. 7268-7278. by Kimberly B. Kegel, Manho Kim, Ellen Sapp, et al.Charmian Mcintyre, Jose G. Castano, Neil Aronin, Marian Difiglia posted to aggregation autophagy cellbiology polyglutamine by inbetweener on 2008-12-09 17:18:38 as
	Huntingtin localization in brains of normal and Huntington's disease patients [My Copy] Annals of Neurology, Vol. 42, No. 4. (1997), pp. 604-612. by E. Sapp, C. Schwarz, K. Chase, et al.P. G. Bhide, A. B. Young, J. Penney, J. P. Vonsattel, N. Aronin, M. Difiglia posted to aggregation hd human huntingtin pathology by inbetweener on 2008-12-09 17:12:59 as
	Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity [My Copy] Nat Genet, Vol. 25, No. 4. (2000), pp. 385-389. by He Li, Shi-Hua Li, Heather Johnston, Peggy F. Shelbourne, Xiao-Jiang Li posted to aggregation axonaltransport hd huntingtin mouse neurodegeneration by inbetweener on 2008-12-07 17:08:56 as
	Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, No. 9. (2 March 2004), pp. 3224-3229. by Wyan-Ching M. Lee, Motojiro Yoshihara, Troy J. Littleton posted to aggregation axonaltransport drosophila hd by inbetweener on 2008-12-07 14:23:29 as
	Interaction of amyotrophic lateral sclerosis (ALS)-related mutant copper-zinc superoxide dismutase with the dynein-dynactin complex contributes to inclusion formation. [My Copy] The Journal of biological chemistry, Vol. 283, No. 33. (15 August 2008), pp. 22795-22805. by Anna-Lena L. Ström, Ping Shi, Fujian Zhang, et al.Jozsef Gal, Renee Kilty, Lawrence J. Hayward, Haining Zhu posted to aggregation als cellbiology inclusion motoneuron mouse sod by inbetweener on 2008-12-06 16:29:13 as along with 1 person ekotelnikova
	Progressive disruption of cellular protein folding in models of polyglutamine diseases. [My Copy] Science (New York, N.Y.), Vol. 311, No. 5766. (10 March 2006), pp. 1471-1474. by T. Gidalevitz, A. Ben-Zvi, K. H. Ho, H. R. Brignull, R. I. Morimoto posted to aggregation folding polyglutamine by inbetweener on 2008-09-20 18:53:59 as along with 2 people and 1 group thegoose2 tharris C. elegans / WormBase
	Suppression of wild-type rhodopsin maturation by mutants linked to autosomal dominant retinitis pigmentosa. [My Copy] The Journal of biological chemistry, Vol. 280, No. 2. (14 January 2005), pp. 1284-1291. by R. S. Rajan, R. R. Kopito posted to aggregation retinitispigmentosa rhodopsin by inbetweener on 2008-09-17 23:07:02 as
	Misfolded proteins partition between two distinct quality control compartments [My Copy] Nature, Vol. 454, No. 7208., pp. 1088-1095. by Daniel Kaganovich, Ron Kopito, Judith Frydman posted to aggregation by inbetweener on 2008-09-17 21:40:28 as along with 1 person reyez
	Bimoclomol: a nontoxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects. [My Copy] Nature medicine, Vol. 3, No. 10. (October 1997), pp. 1150-1154. by L. Vígh, P. N. Literáti, I. Horváth, et al.Z. Török, G. Balogh, A. Glatz, E. Kovács, I. Boros, P. Ferdinándy, B. Farkas, L. Jaszlits, A. Jednákovits, L. Korányi, B. Maresca posted to aggregation arimoclomol chaperones drug heatshock therapy by inbetweener on 2008-09-16 19:51:27 as
	Global Impairment of the Ubiquitin-Proteasome System by Nuclear or Cytoplasmic Protein Aggregates Precedes Inclusion Body Formation [My Copy] Molecular Cell, Vol. 17, No. 3. (4 February 2005), pp. 351-365. by Eric J. Bennett, Neil F. Bence, Rajadas Jayakumar, Ron R. Kopito posted to aggregation inclusions proteinfolding ups by inbetweener on 2008-09-15 21:11:34 as
	Chaperones in control of protein disaggregation. [My Copy] The EMBO journal, Vol. 27, No. 2. (23 January 2008), pp. 328-335. by K. Liberek, A. Lewandowska, S. Zietkiewicz posted to aggregation chaperones heatshock review therapy by inbetweener on 2008-09-15 02:01:40 as
	Pharmacological manipulation of gain-of-function and dominant-negative mechanisms in rhodopsin retinitis pigmentosa. [My Copy] Human molecular genetics (17 July 2008) by Hugo F F. Mendes, Michael E E. Cheetham posted to aggregation heatshock retinitispigmentosa rhodopsin therapy by inbetweener on 2008-09-15 00:05:59 as
	A century-old debate on protein aggregation and neurodegeneration enters the clinic [My Copy] Nature, Vol. 443, No. 7113. (18 October 2006), pp. 774-779. by Peter T. Lansbury, Hilal A. Lashuel posted to aggregation neurodegeneration proteinfolding review therapy by inbetweener on 2008-09-15 00:03:55 as
	Aggresome formation and neurodegenerative diseases: therapeutic implications. [My Copy] Current medicinal chemistry, Vol. 15, No. 1. (2008), pp. 47-60. by J. A. Olzmann, L. Li, L. S. Chin posted to aggregation proteinchemistry review therapy by inbetweener on 2008-09-13 14:27:25 as
	Aggresomes, inclusion bodies and protein aggregation. [My Copy] Trends in cell biology, Vol. 10, No. 12. (December 2000), pp. 524-530. by R. R. Kopito posted to aggregation inclusions proteinfolding review by inbetweener on 2008-09-13 13:43:01 as
	The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation [My Copy] J Cell Sci, Vol. 115, No. 14. (15 July 2002), pp. 2907-2918. by Richard S. Saliba, Peter M. Munro, Philip J. Luthert, Michael E. Cheetham posted to aggregation ayeshapaper retinitispigmentosa rhodopsin by inbetweener on 2008-09-13 13:08:51 as
	A Rhodopsin Mutant Linked to Autosomal Dominant Retinitis Pigmentosa Is Prone to Aggregate and Interacts with the Ubiquitin Proteasome System [My Copy] J. Biol. Chem., Vol. 277, No. 37. (6 September 2002), pp. 34150-34160. by Michelle E. Illing, Rahul S. Rajan, Neil F. Bence, Ron R. Kopito posted to aggregation proteinfolding retinitispigmentosa rhodopsin by inbetweener on 2008-09-13 12:47:45 as
	Mechanisms of cell death in rhodopsin retinitis pigmentosa: implications for therapy [My Copy] Trends in Molecular Medicine, Vol. 11, No. 4. (April 2005), pp. 177-185. by Hugo F. Mendes, Jacqueline van der Spuy, Paul J. Chapple, Michael E. Cheetham posted to aggregation celldeath retina retinitispigmentosa review by inbetweener on 2008-09-13 00:31:35 as
	Polyglutamine neurodegeneration: protein misfolding revisited. [My Copy] Trends in neurosciences (6 September 2008) by Aislinn J J. Williams, Henry L L. Paulson posted to aggregation polyglutamine proteinfolding review by inbetweener on 2008-09-10 18:26:49 as along with 1 person giovanni
	Late stage treatment with Arimoclomol delays disease progression and prevents protein aggregation in the SOD1(G93A) mouse model of ALS. [My Copy] Journal of neurochemistry (30 July 2008) by Bernadett Kalmar, Sergey Novoselov, Anna Gray, Michael E E. Cheetham, Boris Margulis, Linda Greensmith posted to aggregation als arimoclomol mouse sod1 by inbetweener on 2008-09-08 20:51:53 as
	Protein Misfolding, Functional Amyloid, and Human Disease [My Copy] Annual Review of Biochemistry, Vol. 75, No. 1. (2006), pp. 333-366. by Fabrizio Chiti, Christopher M. Dobson posted to aggregation amyloid biochemistry geneticdisease proteinchemistry proteinfolding review by inbetweener on 2008-09-08 20:15:09 as along with 4 people aip lukzky allmensch jennifermbui
	Toxic proteins in neurodegenerative disease. [My Copy] Science (New York, N.Y.), Vol. 296, No. 5575. (14 June 2002), pp. 1991-1995. by J. P. Taylor, J. Hardy, K. H. Fischbeck posted to aggregation neurodegeneration proteinfolding review by inbetweener on 2008-09-08 19:19:17 as
	Therapeutic approaches to polyglutamine diseases: combating protein misfolding and aggregation. [My Copy] Curr Pharm Des, Vol. 12, No. 20. (2006), pp. 2543-2555. by M. Herbst, E. E. Wanker posted to aggregation heatshock polyglutamine review chaperones by inbetweener on 2007-12-04 00:49:44 as
	Global changes to the ubiquitin system in Huntington's disease [My Copy] Nature, Vol. 448, No. 7154., pp. 704-708. by Eric J. Bennett, Thomas A. Shaler, Ben Woodman, et al.Kwon-Yul Ryu, Tatiana S. Zaitseva, Christopher H. Becker, Gillian P. Bates, Howard Schulman, Ron R. Kopito posted to aggregation hd trr-e ups by inbetweener on 2007-08-09 11:40:18 as along with 3 people guhjy littleayesha matstuff
	HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin. [My Copy] J Biol Chem, Vol. 280, No. 48. (2 December 2005), pp. 40282-40292. by A. Iwata, B. E. Riley, J. A. Johnston, R. R. Kopito posted to aggregation autophagy hd hdac htt by inbetweener on 2007-07-16 18:51:10 as
	An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS. [My Copy] Nat Med (7 May 2007) by Rishi Rakhit, Janice Robertson, Christine Vande V. Velde, et al.Patrick Horne, Deborah M M. Ruth, Jennifer Griffin, Don W W. Cleveland, Neil R R. Cashman, Avijit Chakrabartty posted to aggregation als antibody sod by inbetweener on 2007-05-11 13:41:26 as
	Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. [My Copy] Ann Neurol, Vol. 61, No. 5. (May 2007), pp. 427-434. by I. R. Mackenzie, E. H. Bigio, P. G. Ince, et al.F. Geser, M. Neumann, N. J. Cairns, L. K. Kwong, M. S. Forman, J. Ravits, H. Stewart, A. Eisen, L. McClusky, H. A. Kretzschmar, C. M. Monoranu, J. R. Highley, J. Kirby, T. Siddique, P. J. Shaw, V. M. Lee, J. Q. Trojanowski posted to aggregation als fals inclusions pathology by inbetweener on 2007-05-08 16:51:55 as
	Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis [My Copy] Science, Vol. 314, No. 5796. (6 October 2006), pp. 130-133. by Manuela Neumann, Deepak M. Sampathu, Linda K. Kwong, et al.Adam C. Truax, Matthew C. Micsenyi, Thomas T. Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M. Clark, Leo F. Mccluskey, Bruce L. Miller, Eliezer Masliah, Ian R. Mackenzie, Howard Feldman, Wolfgang Feiden, Hans A. Kretzschmar, John Q. Trojanowski, Virginia M. Y. Lee posted to aggregation als inclusions pdf by inbetweener on 2007-05-08 16:50:31 as along with 2 people and 1 group StuartForrest giovanni GeschwindLab
	Aggregation and proteasome: The case of elongated polyglutamine aggregation in spinal and bulbar muscular atrophy. [My Copy] Neurobiol Aging (14 June 2006) by Paola Rusmini, Daniela Sau, Valeria Crippa, et al.Isabella Palazzolo, Francesca Simonini, Elisa Onesto, Luciano Martini, Angelo Poletti posted to aggregation ar proteasome sbma by inbetweener on 2006-10-26 07:41:16 as
	Targeting protein aggregation in neurodegeneration lessons from polyglutamine disorders [My Copy] Expert Opinion on Therapeutic Targets, Vol. 10, No. 4. (August 2006), pp. 505-513. by Weydt, Patrick, La Spada, R. Albert posted to aggregation neurodegeneration polyglutamine review therapy by inbetweener on 2006-10-26 07:31:08 as
	Biologically Active Molecules that Reduce Polyglutamine Aggregation and Toxicity. [My Copy] Hum Mol Genet (23 May 2006) by Urvee A A. Desai, Judit Pallos, Brent R R. Stockwell, Leslie Michels M. Thompson, J Lawrence L. Marsh, Marc I I. Diamond posted to aggregation ar fret hd polyglutamine therapy by inbetweener on 2006-05-25 18:46:34 as
	Ligand-dependent aggregation of polyglutamine-expanded androgen receptor in neuronal cells. [My Copy] Neuroreport, Vol. 13, No. 16. (15 November 2002), pp. 2117-2120. by R. S. Darrington, R. Butler, P. N. Leigh, M. J. McPhaul, J. M. Gallo posted to aggregation ar cellbiology sbma by inbetweener on 2006-04-18 18:12:01 as
	Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. [My Copy] Nature, Vol. 431, No. 7010. (14 October 2004), pp. 805-810. by M. Arrasate, S. Mitra, E. S. Schweitzer, M. R. Segal, S. Finkbeiner posted to aggregation hd inclusion microscopy polyglutamine by inbetweener on 2006-04-05 09:29:12 as
	From the Cover: Pharmacological promotion of inclusion formation: A therapeutic approach for Huntington's and Parkinson's diseases. [My Copy] Proc Natl Acad Sci U S A, Vol. 103, No. 11. (14 March 2006), pp. 4246-4251. by R. A. Bodner, T. F. Outeiro, S. Altmann, et al.M. M. Maxwell, S. H. Cho, B. T. Hyman, P. J. McLean, A. B. Young, D. E. Housman, A. G. Kazantsev posted to aggregation hd pd pdf polyglutamine therapy by inbetweener on 2006-03-21 17:40:37 as
	Heat shock response modulators as therapeutic tools for diseases of protein conformation. [My Copy] J Biol Chem, Vol. 280, No. 39. (30 September 2005), pp. 33097-33100. by S. D. Westerheide, R. I. Morimoto posted to aggregation heatshock neurodegeneration pdf therapy by inbetweener on 2005-11-17 12:47:36 as along with 2 people AstroMicrogliaMania littleayesha
	Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease. [My Copy] Proc Natl Acad Sci U S A, Vol. 102, No. 46. (15 November 2005), pp. 16801-16806. by Masahisa Katsuno, Chen Sang, Hiroaki Adachi, et al.Makoto Minamiyama, Masahiro Waza, Fumiaki Tanaka, Manabu Doyu, Gen Sobue posted to aggregation ar heatshock pdf polyglutamine sbma transgenic by inbetweener on 2005-11-17 12:40:35 as
	17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration [My Copy] Nature Medicine, Vol. 11, No. 10. (11 September 2005), pp. 1088-1095. by Masahiro Waza, Hiroaki Adachi, Masahisa Katsuno, et al.Makoto Minamiyama, Chen Sang, Fumiaki Tanaka, Akira Inukai, Manabu Doyu, Gen Sobue posted to aggregation ar chaperones heatshock pdf polyglutamine sbma by inbetweener on 2005-10-10 11:57:23 as
	Formation of morphologically similar globular aggregates from diverse aggregation-prone proteins in mammalian cells. [My Copy] Proc Natl Acad Sci U S A, Vol. 102, No. 31. (2 August 2005), pp. 10887-10892. by H. Mukai, T. Isagawa, E. Goyama, et al.S. Tanaka, N. F. Bence, A. Tamura, Y. Ono, R. R. Kopito posted to aggregation cellculture hd polyglutamine by inbetweener on 2005-09-26 12:43:31 as
	Progressive phenotype and nuclear accumulation of an amino-terminal cleavage fragment in a transgenic mouse model with inducible expression of full-length mutant huntingtin. [My Copy] Neurobiol Dis (5 September 2005) by Yuji Tanaka, Shuichi Igarashi, Masayuki Nakamura, et al.Juliette Gafni, Cameron Torcassi, Gabrielle Schilling, Danielle Crippen, Jonathan D D. Wood, Akira Sawa, Nancy A A. Jenkins, Neal G G. Copeland, David R R. Borchelt, Christopher A A. Ross, Lisa M M. Ellerby posted to aggregation hd polyglutamine by inbetweener on 2005-09-13 10:48:16 as
	Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation. [My Copy] Proc Natl Acad Sci U S A (2 September 2005) by Atsushi Iwata, John C C. Christianson, Mirella Bucci, et al.Lisa M M. Ellerby, Nobuyuki Nukina, Lysia S S. Forno, Ron R R. Kopito posted to aggregation ar cellculture sbma by inbetweener on 2005-09-06 19:03:19 as along with 1 person yeastbeast

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review	120
ar	116
sbma	86
als	81
mouse	77
motoneuron	74
polyglutamine	68
axonaltransport	56
aggregation	55
heatshock	48
clinical	47
hd	45
therapy	43
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cvcpaper	31
muscle	31
genetics	30
mitochondria	29
cellbiology	26
chaperones	26
pdf	21
transcription	20
cellculture	17
model	16
nmj	16
dynein	15
autophagy	14
calcium	14
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tempreview	14
developmentalbiology	12
mnd	12
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androgen	10
apoptosis	10
drosophila	10
howtoreadapaper	10
human	10
huntingtin	10
pathogenesis	10
sca	10
ups	10
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inclusions	9
pathology	9
proteinfolding	9
rat	9
casereport	8
caspase	8
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retinitispigmentosa	7
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stroke	1
structuralbiology	1
subcellularlocalisation	1
swallowing	1
tau	1
testosterone	1
thermoregulation	1
thesis	1
tips	1
tms	1
tnf	1
toxin	1
transglutaminase	1
translation	1
translational	1
translocation	1
transplant	1
transport	1
trl-library	1
tumour	1
vbm	1
vesicle	1
yeast	1

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