inbetweener's hd [45 articles] Export

Recent papers added to inbetweener's library classified by the tag hd. You can also see everyone's hd.

	Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. [My Copy] Neuron, Vol. 40, No. 1. (25 September 2003), pp. 25-40. by S. Gunawardena, L. S. Her, R. G. Brusch, et al.R. A. Laymon, I. R. Niesman, B. Gordesky-Gold, L. Sintasath, N. M. Bonini, L. S. Goldstein posted to axonaltransport drosophila hd by inbetweener on 2009-06-27 19:53:51 as
	Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. [My Copy] Cell, Vol. 118, No. 1. (9 July 2004), pp. 127-138. by L. R. Gauthier, B. C. Charrin, M. Borrell-Pagès, et al.J. P. Dompierre, H. Rangone, F. P. Cordelières, J. De Mey, M. E. MacDonald, V. Lessmann, S. Humbert, F. Saudou posted to axonaltransport cellculture hd by inbetweener on 2009-06-27 19:49:39 as
	Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro. [My Copy] Molecular and cellular biology, Vol. 24, No. 18. (September 2004), pp. 8195-8209. by E. Trushina, R. B. Dyer, J. D. Badger, et al.D. Ure, L. Eide, D. D. Tran, B. T. Vrieze, V. Legendre-Guillemin, P. S. McPherson, B. S. Mandavilli, B. Van Houten, S. Zeitlin, M. McNiven, R. Aebersold, M. Hayden, J. E. Parisi, E. Seeberg, I. Dragatsis, K. Doyle, A. Bender, C. Chacko, C. T. McMurray posted to axonaltransport cellculture hd by inbetweener on 2009-06-27 19:49:24 as
	Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei. [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, No. 13. (22 June 1999), pp. 7388-7393. by M. V. Karpuj, H. Garren, H. Slunt, et al.D. L. Price, J. Gusella, M. W. Becher, L. Steinman posted to aggregation hd polyglutamine transglutaminase by inbetweener on 2009-05-07 10:42:24 as
	Acetylation targets mutant huntingtin to autophagosomes for degradation. [My Copy] Cell, Vol. 137, No. 1. (3 April 2009), pp. 60-72. by H. Jeong, F. Then, T. J. Melia, et al.J. R. Mazzulli, L. Cui, J. N. Savas, C. Voisine, P. Paganetti, N. Tanese, A. C. Hart, A. Yamamoto, D. Krainc posted to aggregation autophagy hd by inbetweener on 2009-04-14 19:18:53 as
	Overexpression of yeast hsp104 reduces polyglutamine aggregation and prolongs survival of a transgenic mouse model of Huntington's disease. [My Copy] Human molecular genetics, Vol. 14, No. 22. (15 November 2005), pp. 3425-3433. by C. Vacher, L. Garcia-Oroz, D. C. Rubinsztein posted to chaperones hd heatshock model mouse polyglutamine by inbetweener on 2009-04-11 19:31:29 as
	Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin [published erratum appears in Hum Mol Genet 1999 May;8(5):943] [My Copy] Hum. Mol. Genet., Vol. 8, No. 3. (1 March 1999), pp. 397-407. by G. Schilling, M. W. Becher, A. H. Sharp, et al.H. A. Jinnah, K. Duan, J. A. Kotzuk, H. H. Slunt, T. Ratovitski, J. K. Cooper, N. A. Jenkins, N. G. Copeland, D. L. Price, C. A. Ross, D. R. Borchelt posted to aggregate hd model mouse by inbetweener on 2008-12-09 18:29:44 as
	Regulation of Intracellular Accumulation of Mutant Huntingtin by Beclin 1 [My Copy] J. Biol. Chem., Vol. 281, No. 20. (19 May 2006), pp. 14474-14485. by Mamoru Shibata, Tao Lu, Tsuyoshi Furuya, et al.Alexei Degterev, Noboru Mizushima, Tamotsu Yoshimori, Marcy Macdonald, Bruce Yankner, Junying Yuan posted to autophagy genetic hd by inbetweener on 2008-12-09 18:12:19 as
	Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions. [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, No. 32. (9 August 2005), pp. 11402-11407. by E. J. Slow, R. K. Graham, A. P. Osmand, et al.R. S. Devon, G. Lu, Y. Deng, J. Pearson, K. Vaid, N. Bissada, R. Wetzel, B. R. Leavitt, M. R. Hayden posted to aggregation hd huntingtin inclusions model mouse neurodegeneration by inbetweener on 2008-12-09 17:54:52 as
	Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. [My Copy] Nature genetics, Vol. 36, No. 6. (June 2004), pp. 585-595. by B. Ravikumar, C. Vacher, Z. Berger, et al.J. E. Davies, S. Luo, L. G. Oroz, F. Scaravilli, D. F. Easton, R. Duden, C. J. O'Kane, D. C. Rubinsztein posted to autophagy drosophila hd mouse by inbetweener on 2008-12-09 17:30:10 as
	Huntingtons disease: degradation of mutant huntingtin by autophagy [My Copy] FEBS Journal, Vol. 275, No. 17. (September 2008), pp. 4263-4270. by Sarkar, Sovan, Rubinsztein, C. David posted to aggregation autophagy hd proteindegradation review by inbetweener on 2008-12-09 17:19:51 as
	Huntingtin localization in brains of normal and Huntington's disease patients [My Copy] Annals of Neurology, Vol. 42, No. 4. (1997), pp. 604-612. by E. Sapp, C. Schwarz, K. Chase, et al.P. G. Bhide, A. B. Young, J. Penney, J. P. Vonsattel, N. Aronin, M. Difiglia posted to aggregation hd human huntingtin pathology by inbetweener on 2008-12-09 17:12:59 as
	Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. [My Copy] Cell, Vol. 87, No. 3. (1 November 1996), pp. 493-506. by L. Mangiarini, K. Sathasivam, M. Seller, et al.B. Cozens, A. Harper, C. Hetherington, M. Lawton, Y. Trottier, H. Lehrach, S. W. Davies, G. P. Bates posted to hd model mouse by inbetweener on 2008-12-09 16:06:30 as along with 1 person stevezhang
	Huntingtin Aggregate-Associated Axonal Degeneration is an Early Pathological Event in Huntington's Disease Mice [My Copy] J. Neurosci., Vol. 21, No. 21. (1 November 2001), pp. 8473-8481. by He Li, Shi-Hua Li, Zhao-Xue Yu, Peggy Shelbourne, Xiao-Jiang Li posted to axonaltransport hd huntingtin mouse pathology by inbetweener on 2008-12-07 17:16:24 as
	Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity [My Copy] Nat Genet, Vol. 25, No. 4. (2000), pp. 385-389. by He Li, Shi-Hua Li, Heather Johnston, Peggy F. Shelbourne, Xiao-Jiang Li posted to aggregation axonaltransport hd huntingtin mouse neurodegeneration by inbetweener on 2008-12-07 17:08:56 as
	Axonal transport of N-terminal huntingtin suggests early pathology of corticostriatal projections in Huntington disease. [My Copy] Journal of neuropathology and experimental neurology, Vol. 58, No. 2. (February 1999), pp. 165-173. by E. Sapp, J. Penney, A. Young, N. Aronin, J. P. Vonsattel, M. DiFiglia posted to axonaltransport hd human huntingtin pathology by inbetweener on 2008-12-07 17:06:48 as
	Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, No. 9. (2 March 2004), pp. 3224-3229. by Wyan-Ching M. Lee, Motojiro Yoshihara, Troy J. Littleton posted to aggregation axonaltransport drosophila hd by inbetweener on 2008-12-07 14:23:29 as
	Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain [My Copy] Science, Vol. 277, No. 5334. (26 September 1997), pp. 1990-1993. by Marian Difiglia, Ellen Sapp, Kathryn O. Chase, et al.Stephen W. Davies, Gillian P. Bates, J. P. Vonsattel, Neil Aronin posted to axonaltransport hd huntingtin inclusions by inbetweener on 2008-12-07 14:18:24 as
	Nucleocytoplasmic trafficking and transcription effects of huntingtin in Huntington's disease [My Copy] Progress in Neurobiology In Chromatin Dysfunction in Huntington's Disease, Vol. 83, No. 4. (November 2007), pp. 211-227. by Ray Truant, Randy S. Atwal, Anjee Burtnik posted to hd nucleus transcription by inbetweener on 2008-09-18 00:06:51 as
	Global changes to the ubiquitin system in Huntington's disease [My Copy] Nature, Vol. 448, No. 7154., pp. 704-708. by Eric J. Bennett, Thomas A. Shaler, Ben Woodman, et al.Kwon-Yul Ryu, Tatiana S. Zaitseva, Christopher H. Becker, Gillian P. Bates, Howard Schulman, Ron R. Kopito posted to aggregation hd trr-e ups by inbetweener on 2007-08-09 11:40:18 as along with 3 people guhjy littleayesha matstuff
	PGC-1alpha, a new therapeutic target in Huntington's disease? [My Copy] Cell, Vol. 127, No. 3. (3 November 2006), pp. 465-468. by J. K. McGill, M. F. Beal posted to hd mitochondria review by inbetweener on 2007-07-19 15:50:04 as along with 1 person giovanni
	HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin. [My Copy] J Biol Chem, Vol. 280, No. 48. (2 December 2005), pp. 40282-40292. by A. Iwata, B. E. Riley, J. A. Johnston, R. R. Kopito posted to aggregation autophagy hd hdac htt by inbetweener on 2007-07-16 18:51:10 as
	Huntingtin Interacting Proteins Are Genetic Modifiers of Neurodegeneration. [My Copy] PLoS Genet, Vol. 3, No. 5. (11 May 2007) by Linda S S. Kaltenbach, Eliana Romero, Robert R R. Becklin, et al.Rakesh Chettier, Russell Bell, Amit Phansalkar, Andrew Strand, Cameron Torcassi, Justin Savage, Anthony Hurlburt, Guang-Ho H. Cha, Lubna Ukani, Cindy Lou L. Chepanoske, Yuejun Zhen, Sudhir Sahasrabudhe, James Olson, Cornelia Kurschner, Lisa M M. Ellerby, John M M. Peltier, Juan Botas, Robert E E. Hughes posted to hd hip neurodegeneration polyglutamine by inbetweener on 2007-05-17 16:56:38 as
	Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons. [My Copy] Neurobiol Dis, Vol. 22, No. 2. (May 2006), pp. 388-400. by D. T. Chang, G. L. Rintoul, S. Pandipati, I. J. Reynolds posted to axonaltransport cellculture hd mitochondria polyglutamine by inbetweener on 2007-04-25 14:36:10 as
	Mitochondrial dysfunction in Huntingtons disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice [My Copy] Journal of Neurochemistry, Vol. 101, No. 1. (April 2007), pp. 241-249. by Oliveira, M. A. Jorge, Jekabsons, et al.B. Mika, Chen, Sylvia, Lin, Amy, Rego, A. Cristina, Goncalves, Jorge, Ellerby, M. Lisa, Nicholls, G. David posted to calcium hd mitochondria mouse polyglutamine by inbetweener on 2007-03-31 16:39:23 as
	The 1st 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis. [My Copy] Hum Mol Genet (29 November 2006) by Erica Rockabrand, Natalia Slepko, Antonello Pantalone, et al.Vidya N N. Nukala, Aleksey Kazantsev, J Lawrence L. Marsh, Patrick G G. Sullivan, Joan S S. Steffan, Stefano L L. Sensi, Leslie Michels M. Thompson posted to calcium hd polyglutamine subcellularlocalisation by inbetweener on 2006-12-15 17:25:14 as
	Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism. [My Copy] J Neurosci, Vol. 26, No. 49. (6 December 2006), pp. 12748-12757. by D. del Toro, J. M. Canals, S. Ginés, M. Kojima, G. Egea, J. Alberch posted to golgi growthfactors hd polyglutamine by inbetweener on 2006-12-15 17:14:33 as
	Huntingtin inhibits caspase-3 activation [My Copy] The EMBO Journal, Vol. aop, No. current. (23 November 2006) by Yu Zhang, Blair R. Leavitt, Jeremy M. van Raamsdonk, et al.Ioannis Dragatsis, Dan Goldowitz, Marcy E. Macdonald, Michael R. Hayden, Robert M. Friedlander posted to apoptosis caspase hd by inbetweener on 2006-11-26 12:08:37 as
	Deranged neuronal calcium signaling and Huntington disease [My Copy] Biochemical and Biophysical Research Communications, Vol. 322, No. 4. (1 October 2004), pp. 1310-1317. by Ilya Bezprozvanny, Michael R. Hayden posted to calcium hd polyglutamine by inbetweener on 2006-10-30 13:49:28 as
	Mitochondrial-Dependent Ca2+ Handling in Huntington's Disease Striatal Cells: Effect of Histone Deacetylase Inhibitors. [My Copy] J Neurosci, Vol. 26, No. 43. (25 October 2006), pp. 11174-11186. by Jorge M A M. Oliveira, Sylvia Chen, Sandra Almeida, et al.Rebeccah Riley, Jorge Gonçalves, Catarina R R. Oliveira, Michael R R. Hayden, David G G. Nicholls, Lisa M M. Ellerby, A Cristina C. Rego posted to calcium hd hdac mitochondria polyglutamine by inbetweener on 2006-10-27 15:13:33 as
	Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration. [My Copy] Cell Metab (18 October 2006) by Patrick Weydt, Victor V V. Pineda, Anne E E. Torrence, et al.Randell T T. Libby, Terrence F F. Satterfield, Eduardo R R. Lazarowski, Merle L L. Gilbert, Gregory J J. Morton, Theodor K K. Bammler, Andrew D D. Strand, Libin Cui, Richard P P. Beyer, Courtney N N. Easley, Annette C C. Smith, Dimitri Krainc, Serge Luquet, Ian R R. Sweet, Michael W W. Schwartz, Albert R R. La Spada posted to hd metabolic mitochondria mouse neurodegeneration polyglutamine thermoregulation by inbetweener on 2006-10-26 07:29:42 as along with 1 person mmarinin
	Cytotoxicity of a Mutant Huntingtin Fragment in Yeast Involves Early Alterations in Mitochondrial OXPHOS Complex II and III. [My Copy] Hum Mol Genet (12 September 2006) by Asun Solans, Andrea Zambrano, Mayra Rodríguez, Antoni Barrientos posted to cytotoxicity hd mitochondria polyglutamine yeast by inbetweener on 2006-09-18 13:18:34 as
	The likelihood of being affected with Huntington disease by a particular age, for a specific CAG size. [My Copy] Am J Hum Genet, Vol. 60, No. 5. (May 1997), pp. 1202-1210. by R. R. Brinkman, M. M. Mezei, J. Theilmann, E. Almqvist, M. R. Hayden posted to clinical genetics hd by inbetweener on 2006-09-14 18:02:56 as
	Biologically Active Molecules that Reduce Polyglutamine Aggregation and Toxicity. [My Copy] Hum Mol Genet (23 May 2006) by Urvee A A. Desai, Judit Pallos, Brent R R. Stockwell, Leslie Michels M. Thompson, J Lawrence L. Marsh, Marc I I. Diamond posted to aggregation ar fret hd polyglutamine therapy by inbetweener on 2006-05-25 18:46:34 as
	Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. [My Copy] Nature, Vol. 431, No. 7010. (14 October 2004), pp. 805-810. by M. Arrasate, S. Mitra, E. S. Schweitzer, M. R. Segal, S. Finkbeiner posted to aggregation hd inclusion microscopy polyglutamine by inbetweener on 2006-04-05 09:29:12 as
	From the Cover: Pharmacological promotion of inclusion formation: A therapeutic approach for Huntington's and Parkinson's diseases. [My Copy] Proc Natl Acad Sci U S A, Vol. 103, No. 11. (14 March 2006), pp. 4246-4251. by R. A. Bodner, T. F. Outeiro, S. Altmann, et al.M. M. Maxwell, S. H. Cho, B. T. Hyman, P. J. McLean, A. B. Young, D. E. Housman, A. G. Kazantsev posted to aggregation hd pd pdf polyglutamine therapy by inbetweener on 2006-03-21 17:40:37 as
	Formation of morphologically similar globular aggregates from diverse aggregation-prone proteins in mammalian cells. [My Copy] Proc Natl Acad Sci U S A, Vol. 102, No. 31. (2 August 2005), pp. 10887-10892. by H. Mukai, T. Isagawa, E. Goyama, et al.S. Tanaka, N. F. Bence, A. Tamura, Y. Ono, R. R. Kopito posted to aggregation cellculture hd polyglutamine by inbetweener on 2005-09-26 12:43:31 as
	Progressive phenotype and nuclear accumulation of an amino-terminal cleavage fragment in a transgenic mouse model with inducible expression of full-length mutant huntingtin. [My Copy] Neurobiol Dis (5 September 2005) by Yuji Tanaka, Shuichi Igarashi, Masayuki Nakamura, et al.Juliette Gafni, Cameron Torcassi, Gabrielle Schilling, Danielle Crippen, Jonathan D D. Wood, Akira Sawa, Nancy A A. Jenkins, Neal G G. Copeland, David R R. Borchelt, Christopher A A. Ross, Lisa M M. Ellerby posted to aggregation hd polyglutamine by inbetweener on 2005-09-13 10:48:16 as
	History of genetic disease: The molecular genetics of Huntington disease - a history. [My Copy] Nat Rev Genet (31 August 2005) by Gillian P P. Bates posted to hd review by inbetweener on 2005-09-05 11:59:25 as along with 1 person and 1 group cgreal CGREL
	Inhibition of polyglutamine aggregation in R6/2 HD brain slices-complex dose-response profiles. [My Copy] Neurobiol Dis, Vol. 8, No. 6. (December 2001), pp. 1017-1026. by D. L. Smith, R. Portier, B. Woodman, et al.E. Hockly, A. Mahal, W. E. Klunk, X. J. Li, E. Wanker, K. D. Murray, G. P. Bates posted to aggregation cellculture hd therapy by inbetweener on 2005-08-23 11:29:27 as
	Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series. [My Copy] EMBO Rep, Vol. 5, No. 10. (October 2004), pp. 958-963. by C. Landles, G. P. Bates posted to cellbiology hd pathogenesis polyglutamine review by inbetweener on 2005-08-23 11:23:14 as
	Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: implications for mutant huntingtin toxicity. [My Copy] J Cell Biol, Vol. 169, No. 4. (23 May 2005), pp. 647-656. by S. Luo, C. Vacher, J. E. Davies, D. C. Rubinsztein posted to caspase cdk5 hd polyglutamine by inbetweener on 2005-08-10 16:53:04 as
	Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport. [My Copy] Neuron, Vol. 40, No. 1. (25 September 2003), pp. 41-52. by G. Szebenyi, G. A. Morfini, A. Babcock, et al.M. Gould, K. Selkoe, D. L. Stenoien, M. Young, P. W. Faber, M. E. MacDonald, M. J. McPhaul, S. T. Brady posted to ar axonaltransport hd polyglutamine sbma by inbetweener on 2005-08-08 18:55:44 as
	SUMO modification of Huntingtin and Huntington's disease pathology. [My Copy] Science, Vol. 304, No. 5667. (2 April 2004), pp. 100-104. by J. S. Steffan, N. Agrawal, J. Pallos, et al.E. Rockabrand, L. C. Trotman, N. Slepko, K. Illes, T. Lukacsovich, Y. Z. Zhu, E. Cattaneo, P. P. Pandolfi, L. M. Thompson, J. L. Marsh posted to hd polyglutamine sumo by inbetweener on 2005-08-08 18:20:11 as
	Dynein mutations impair autophagic clearance of aggregate-prone proteins [My Copy] Nature Genetics, Vol. 37, No. 7. (26 June 2005), pp. 771-776. by Brinda Ravikumar, Abraham Acevedo-Arozena, Sara Imarisio, et al.Zdenek Berger, Coralie Vacher, Cahir J. O'Kane, Steve D. M. Brown, David C. Rubinsztein posted to autophagy axonaltransport dynein hd loa polyglutamine by inbetweener on 2005-08-08 17:07:24 as

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review	120
ar	116
sbma	86
als	81
mouse	77
motoneuron	74
polyglutamine	68
axonaltransport	56
aggregation	55
heatshock	48
clinical	47
hd	45
therapy	43
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cvcpaper	31
muscle	31
genetics	30
mitochondria	29
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pdf	21
transcription	20
cellculture	17
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ups	10
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stroke	1
structuralbiology	1
subcellularlocalisation	1
swallowing	1
tau	1
testosterone	1
thermoregulation	1
thesis	1
tips	1
tms	1
tnf	1
toxin	1
transglutaminase	1
translation	1
translational	1
translocation	1
transplant	1
transport	1
trl-library	1
tumour	1
vbm	1
vesicle	1
yeast	1

inbetweener's hd [45 articles] Export

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