Constitutive heterochromatin: a surprising variety of expressed sequences Export

@article{citeulike:4483450, abstract = {Abstract\ \ The organization of chromosomes into euchromatin and heterochromatin is amongst the most important and enigmatic aspects of genome evolution. Constitutive heterochromatin is a basic yet still poorly understood component of eukaryotic chromosomes, and its molecular characterization by means of standard genomic approaches is intrinsically difficult. Although recent evidence indicates that the presence of transcribed genes in constitutive heterochromatin is a conserved trait that accompanies the evolution of eukaryotic genomes, the term heterochromatin is still considered by many as synonymous of gene silencing. In this paper, we comprehensively review data that provide a clearer picture of transcribed sequences within constitutive heterochromatin, with a special emphasis on Drosophila and humans.}, author = {Dimitri, Patrizio and Caizzi, Ruggiero and Giordano, Ennio and Carmela and Lattanzi, Giovanna and Biamonti, Giuseppe}, citeulike-article-id = {4483450}, citeulike-linkout-0 = {http://dx.doi.org/10.1007/s00412-009-0211-y}, citeulike-linkout-1 = {http://www.springerlink.com/content/k33512w631767766}, doi = {10.1007/s00412-009-0211-y}, journal = {Chromosoma}, keywords = {chromatin-review, evolution, genome-organization}, posted-at = {2009-06-29 14:23:15}, priority = {5}, title = {Constitutive heterochromatin: a surprising variety of expressed sequences}, url = {http://dx.doi.org/10.1007/s00412-009-0211-y} }

TY - JOUR ID - citeulike:4483450 L3 - citeulike-article-id:4483450 N2 - Abstract  The organization of chromosomes into euchromatin and heterochromatin is amongst the most important and enigmatic aspects of genome evolution. Constitutive heterochromatin is a basic yet still poorly understood component of eukaryotic chromosomes, and its molecular characterization by means of standard genomic approaches is intrinsically difficult. Although recent evidence indicates that the presence of transcribed genes in constitutive heterochromatin is a conserved trait that accompanies the evolution of eukaryotic genomes, the term heterochromatin is still considered by many as synonymous of gene silencing. In this paper, we comprehensively review data that provide a clearer picture of transcribed sequences within constitutive heterochromatin, with a special emphasis on Drosophila and humans. JF - Chromosoma TI - Constitutive heterochromatin: a surprising variety of expressed sequences KW - chromatin-review KW - evolution KW - genome-organization AU - Dimitri, Patrizio AU - Caizzi, Ruggiero AU - Giordano, Ennio AU - Carmela AU - Lattanzi, Giovanna AU - Biamonti, Giuseppe UR - http://dx.doi.org/10.1007/s00412-009-0211-y ER -