Understanding memory through hippocampal remapping Export

@article{citeulike:3176997, abstract = {Memory interference is a common cause of forgetting. Interference is a byproduct of the need to balance the formation of well-differentiated representations against the ability to retrieve memories from cues that are not identical to the original experience. How the brain accomplishes this has remained elusive. Here we review how insights can be gained from studies of an apparently unrelated phenomenon in the rodent brain - remapping in hippocampal place cells. Remapping refers to the formation of distinct representations in populations of place cells after minor changes in inputs to the hippocampus. Remapping might reflect processes involved generally in decorrelation of overlapping signals. These processes might be crucial for storing large numbers of similar experiences with only minimal interference.}, author = {Colgin, Laura L. and Moser, Edvard I. and Moser, May-Britt}, citeulike-article-id = {3176997}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.tins.2008.06.008}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0166223608001677}, citeulike-linkout-2 = {http://www.sciencedirect.com/science/article/B6T0V-4T50CB8-1/2/551051fae864654f0324f8672187bbff}, doi = {10.1016/j.tins.2008.06.008}, journal = {Trends in Neurosciences}, keywords = {alzheimer, dementia, molecular}, month = {September}, number = {9}, pages = {469--477}, posted-at = {2008-08-31 20:21:44}, priority = {2}, title = {Understanding memory through hippocampal remapping}, url = {http://dx.doi.org/10.1016/j.tins.2008.06.008}, volume = {31}, year = {2008} }

TY - JOUR ID - citeulike:3176997 L3 - citeulike-article-id:3176997 N2 - Memory interference is a common cause of forgetting. Interference is a byproduct of the need to balance the formation of well-differentiated representations against the ability to retrieve memories from cues that are not identical to the original experience. How the brain accomplishes this has remained elusive. Here we review how insights can be gained from studies of an apparently unrelated phenomenon in the rodent brain - remapping in hippocampal place cells. Remapping refers to the formation of distinct representations in populations of place cells after minor changes in inputs to the hippocampus. Remapping might reflect processes involved generally in decorrelation of overlapping signals. These processes might be crucial for storing large numbers of similar experiences with only minimal interference. IS - 9 JF - Trends in Neurosciences EP - 477 TI - Understanding memory through hippocampal remapping VL - 31 SP - 469 KW - alzheimer KW - dementia KW - molecular AU - Colgin, Laura AU - Moser, Edvard AU - Moser, May-Britt PY - 2008/09// UR - http://dx.doi.org/10.1016/j.tins.2008.06.008 ER -