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Entropy of complex relevant components of Boolean networks

by: Peter Krawitz, Ilya Shmulevich
Physical Review E, Vol. 76, No. 3. (Sep 2007), 036115, doi:10.1103/physreve.76.036115  Key: citeulike:9243942

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Abstract

Boolean network models of strongly connected modules are capable of capturing the high regulatory complexity of many biological gene regulatory circuits. We study numerically the previously introduced basin entropy, a parameter for the dynamical uncertainty or information storage capacity of a network as well as the average transient time in random relevant components as a function of their connectivity. We also demonstrate that basin entropy can be estimated from time-series data and is therefore also applicable to nondeterministic networks models.


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