Attention: oscillations and neuropharmacology. Export

@article{citeulike:5279243, abstract = {Attention is a rich psychological and neurobiological construct that influences almost all aspects of cognitive behaviour. It enables enhanced processing of behaviourally relevant stimuli at the expense of irrelevant stimuli. At the cellular level, rhythmic synchronization at local and long-range spatial scales complements the attention-induced firing rate changes of neurons. The former is hypothesized to enable efficient communication between neuronal ensembles tuned to spatial and featural aspects of the attended stimulus. Recent modelling studies suggest that the rhythmic synchronization in the gamma range may be mediated by a fine balance between N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate postsynaptic currents, whereas other studies have highlighted the possible contribution of the neuromodulator acetylcholine. This review summarizes some recent modelling and experimental studies investigating mechanisms of attention in sensory areas and discusses possibilities of how glutamatergic and cholinergic systems could contribute to increased processing abilities at the cellular and network level during states of top-down attention.}, address = {Computational Neuroscience Group, Department of Technology, Universitat Pompeu Fabra, Barcelona, Spain; Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK}, author = {Deco, Gustavo and Thiele, Alexander}, citeulike-article-id = {5279243}, citeulike-linkout-0 = {http://dx.doi.org/10.1111/j.1460-9568.2009.06833.x}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/19614749}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=19614749}, citeulike-linkout-3 = {http://www3.interscience.wiley.com/cgi-bin/abstract/122513151/ABSTRACT}, day = {15}, doi = {10.1111/j.1460-9568.2009.06833.x}, issn = {1460-9568}, journal = {The European journal of neuroscience}, keywords = {attention, oscillation, review}, month = {August}, number = {3}, pages = {347--354}, posted-at = {2009-07-27 09:29:22}, priority = {2}, title = {Attention: oscillations and neuropharmacology.}, url = {http://dx.doi.org/10.1111/j.1460-9568.2009.06833.x}, volume = {30}, year = {2009} }

TY - JOUR ID - citeulike:5279243 L3 - citeulike-article-id:5279243 N2 - Attention is a rich psychological and neurobiological construct that influences almost all aspects of cognitive behaviour. It enables enhanced processing of behaviourally relevant stimuli at the expense of irrelevant stimuli. At the cellular level, rhythmic synchronization at local and long-range spatial scales complements the attention-induced firing rate changes of neurons. The former is hypothesized to enable efficient communication between neuronal ensembles tuned to spatial and featural aspects of the attended stimulus. Recent modelling studies suggest that the rhythmic synchronization in the gamma range may be mediated by a fine balance between N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate postsynaptic currents, whereas other studies have highlighted the possible contribution of the neuromodulator acetylcholine. This review summarizes some recent modelling and experimental studies investigating mechanisms of attention in sensory areas and discusses possibilities of how glutamatergic and cholinergic systems could contribute to increased processing abilities at the cellular and network level during states of top-down attention. IS - 3 JF - The European journal of neuroscience SN - 1460-9568 AD - Computational Neuroscience Group, Department of Technology, Universitat Pompeu Fabra, Barcelona, Spain; Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK EP - 354 TI - Attention: oscillations and neuropharmacology. VL - 30 SP - 347 KW - attention KW - oscillation KW - review AU - Deco, Gustavo AU - Thiele, Alexander PY - 2009/08/15/ UR - http://dx.doi.org/10.1111/j.1460-9568.2009.06833.x ER -