CAPweb: a bioinformatics CGH array Analysis Platform. Export

@article{citeulike:792345, abstract = {Assessing variations in DNA copy number is crucial for understanding constitutional or somatic diseases, particularly cancers. The recently developed array-CGH (comparative genomic hybridization) technology allows this to be investigated at the genomic level. We report the availability of a web tool for analysing array-CGH data. CAPweb (CGH array Analysis Platform on the Web) is intended as a user-friendly tool enabling biologists to completely analyse CGH arrays from the raw data to the visualization and biological interpretation. The user typically performs the following bioinformatics steps of a CGH array project within CAPweb: the secure upload of the results of CGH array image analysis and of the array annotation (genomic position of the probes); first level analysis of each array, including automatic normalization of the data (for correcting experimental biases), breakpoint detection and status assignment (gain, loss or normal); validation or deletion of the analysis based on a summary report and quality criteria; visualization and biological analysis of the genomic profiles and results through a user-friendly interface. CAPweb is accessible at http://bioinfo.curie.fr/CAPweb.}, address = {Institut Curie, Service Bioinformatique 26 rue d'Ulm, 75248 Paris Cedex 05, France. capweb@curie.fr}, author = {Liva, St\'{e}phane and Hup\'{e}, Philippe and Neuvial, Pierre and Brito, Isabel and Viara, Eric and La Rosa, Philippe and Barillot, Emmanuel}, citeulike-article-id = {792345}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/nar/gkl215}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/16845053}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=16845053}, day = {1}, doi = {10.1093/nar/gkl215}, issn = {1362-4962}, journal = {Nucleic acids research}, keywords = {algorithm, analysis, cgh, software}, month = {July}, number = {Web Server issue}, posted-at = {2006-08-25 09:20:21}, priority = {2}, title = {CAPweb: a bioinformatics CGH array Analysis Platform.}, url = {http://dx.doi.org/10.1093/nar/gkl215}, volume = {34}, year = {2006} }

TY - JOUR ID - citeulike:792345 L3 - citeulike-article-id:792345 N2 - Assessing variations in DNA copy number is crucial for understanding constitutional or somatic diseases, particularly cancers. The recently developed array-CGH (comparative genomic hybridization) technology allows this to be investigated at the genomic level. We report the availability of a web tool for analysing array-CGH data. CAPweb (CGH array Analysis Platform on the Web) is intended as a user-friendly tool enabling biologists to completely analyse CGH arrays from the raw data to the visualization and biological interpretation. The user typically performs the following bioinformatics steps of a CGH array project within CAPweb: the secure upload of the results of CGH array image analysis and of the array annotation (genomic position of the probes); first level analysis of each array, including automatic normalization of the data (for correcting experimental biases), breakpoint detection and status assignment (gain, loss or normal); validation or deletion of the analysis based on a summary report and quality criteria; visualization and biological analysis of the genomic profiles and results through a user-friendly interface. CAPweb is accessible at http://bioinfo.curie.fr/CAPweb. IS - Web Server issue JF - Nucleic acids research SN - 1362-4962 AD - Institut Curie, Service Bioinformatique 26 rue d'Ulm, 75248 Paris Cedex 05, France. capweb@curie.fr TI - CAPweb: a bioinformatics CGH array Analysis Platform. VL - 34 KW - algorithm KW - analysis KW - cgh KW - software AU - Liva, Stéphane AU - Hupé, Philippe AU - Neuvial, Pierre AU - Brito, Isabel AU - Viara, Eric AU - La Rosa, Philippe AU - Barillot, Emmanuel PY - 2006/07/01/ UR - http://dx.doi.org/10.1093/nar/gkl215 ER -