On the mechanism of cerebellar contributions to cognition Export

@article{citeulike:3135414, abstract = {The cerebellum is highly stereotyped in its cellular circuitry. Output neurons in the nuclei with one exception excite their downstream targets in other parts of the nervous system. Yet the much more voluminous cerebellar cortex inhibits these output neurons. This has suggested that the desired output activity pattern is achieved by removing all unwanted activity patterns (‘sculpting’). Lesions of the lateral cerebellum impair cognitive functions including speech. These lateral portions are active during imagined as well as overt movements. Imagined movements could be used to time task performances in the absence of an external clock. The intrinsic circuitry suggests that the cerebellar cortex links together and combines nuclear output activities. A linkage mechanism is consistent with the motor deficits in coordination after midline vermal section in humans and Purkinje cell recording in trained animals. The lateral cerebellum, which projects to frontal and parietal ‘association’ cortex, may link together cerebral ‘cognitive units’ as a substrate for coordinated thought.}, author = {Thach, W. T.}, citeulike-article-id = {3135414}, citeulike-linkout-0 = {http://dx.doi.org/10.1080/14734220701373530}, doi = {10.1080/14734220701373530}, journal = {The Cerebellum}, keywords = {cerebellar, cerebellum, cognition}, number = {3}, pages = {163--167}, posted-at = {2008-08-19 07:39:57}, priority = {2}, publisher = {Informa Healthcare}, title = {On the mechanism of cerebellar contributions to cognition}, url = {http://dx.doi.org/10.1080/14734220701373530}, volume = {6}, year = {2007} }

TY - JOUR ID - citeulike:3135414 L3 - citeulike-article-id:3135414 N2 - The cerebellum is highly stereotyped in its cellular circuitry. Output neurons in the nuclei with one exception excite their downstream targets in other parts of the nervous system. Yet the much more voluminous cerebellar cortex inhibits these output neurons. This has suggested that the desired output activity pattern is achieved by removing all unwanted activity patterns (‘sculpting’). Lesions of the lateral cerebellum impair cognitive functions including speech. These lateral portions are active during imagined as well as overt movements. Imagined movements could be used to time task performances in the absence of an external clock. The intrinsic circuitry suggests that the cerebellar cortex links together and combines nuclear output activities. A linkage mechanism is consistent with the motor deficits in coordination after midline vermal section in humans and Purkinje cell recording in trained animals. The lateral cerebellum, which projects to frontal and parietal ‘association’ cortex, may link together cerebral ‘cognitive units’ as a substrate for coordinated thought. IS - 3 JF - The Cerebellum EP - 167 TI - On the mechanism of cerebellar contributions to cognition PB - Informa Healthcare VL - 6 SP - 163 KW - cerebellar KW - cerebellum KW - cognition AU - Thach, WT PY - 2007/// UR - http://dx.doi.org/10.1080/14734220701373530 ER -