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Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease

by: Gabriel A. Kwong, Geoffrey von Maltzahn, Gayathree Murugappan, Omar Abudayyeh, Steven Mo, Ioannis A. Papayannopoulos, Deanna Y. Sverdlov, Susan B. Liu, Andrew D. Warren, Yury Popov, Detlef Schuppan, Sangeeta N. Bhatia
Nature Biotechnology, Vol. 31, No. 1. (16 December 2012), pp. 63-70, doi:10.1038/nbt.2464  Key: citeulike:11890120

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Abstract

Kwong et al. use nanoparticles coated with protease substrates to generate mass-encoded synthetic biomarkers for sensitive detection of fibrosis and cancer in mice.


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