Rapid isotropic diffusion mapping without susceptibility artifacts: whole brain studies using diffusion-weighted single-shot STEAM MR imaging. Export

@article{citeulike:1044862, abstract = {A subsecond magnetic resonance imaging (MRI) technique for isotropic diffusion mapping is described which, in contrast to echo-planar imaging (EPI), is insensitive to resonance offsets, i.e., tissue susceptibility differences, magnetic field inhomogeneities, and chemical shifts. It combines a diffusion-weighted (DW) spin-echo preparation period and a high-speed stimulated echo acquisition mode (STEAM) MRI sequence and yields single-shot images within measuring times of 559 msec (80 echoes). Here, diffusion encoding involved one scan without DW, three DW scans with b = 490 sec mm(-2), and three DW scans with b = 1000 sec mm(-2) (orthogonal gradient orientations). An automated on-line evaluation resulted in isotropic DW images as well as ADC maps (trace of the diffusion tensor). Experiments at 2.0 T covered the brain of healthy subjects in 20 contiguous sections of 6 mm thickness and 2.0 x 2.0 mm(2) in-plane resolution within a total measuring time of 78 sec. High-resolution studies at 1.0 x 1.0 mm(2) (interpolated from 2.0 x 1.0 mm(2) acquisitions) were obtained within 5 min 13 sec using four averages. In comparison with EPI, DW single-shot STEAM MRI exhibits only about half the SNR, but completely avoids regional signal losses, high intensity artifacts, and geometric distortions.}, address = {Biomedizinische NMR Forschungs GmbH am Max-Planck-Institut f\"{u}r biophysikalische Chemie, G\"{o}ttingen, Germany.}, author = {Nolte, U. G. and Finsterbusch, J. and Frahm, J.}, citeulike-article-id = {1044862}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/11064408}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=11064408}, issn = {0740-3194}, journal = {Magn Reson Med}, keywords = {distorsion-geometric, dti, sequence}, month = {November}, number = {5}, pages = {731--736}, posted-at = {2007-01-16 21:52:16}, priority = {2}, title = {Rapid isotropic diffusion mapping without susceptibility artifacts: whole brain studies using diffusion-weighted single-shot STEAM MR imaging.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/11064408}, volume = {44}, year = {2000} }

TY - JOUR ID - citeulike:1044862 L3 - citeulike-article-id:1044862 N2 - A subsecond magnetic resonance imaging (MRI) technique for isotropic diffusion mapping is described which, in contrast to echo-planar imaging (EPI), is insensitive to resonance offsets, i.e., tissue susceptibility differences, magnetic field inhomogeneities, and chemical shifts. It combines a diffusion-weighted (DW) spin-echo preparation period and a high-speed stimulated echo acquisition mode (STEAM) MRI sequence and yields single-shot images within measuring times of 559 msec (80 echoes). Here, diffusion encoding involved one scan without DW, three DW scans with b = 490 sec mm(-2), and three DW scans with b = 1000 sec mm(-2) (orthogonal gradient orientations). An automated on-line evaluation resulted in isotropic DW images as well as ADC maps (trace of the diffusion tensor). Experiments at 2.0 T covered the brain of healthy subjects in 20 contiguous sections of 6 mm thickness and 2.0 x 2.0 mm(2) in-plane resolution within a total measuring time of 78 sec. High-resolution studies at 1.0 x 1.0 mm(2) (interpolated from 2.0 x 1.0 mm(2) acquisitions) were obtained within 5 min 13 sec using four averages. In comparison with EPI, DW single-shot STEAM MRI exhibits only about half the SNR, but completely avoids regional signal losses, high intensity artifacts, and geometric distortions. IS - 5 JF - Magn Reson Med SN - 0740-3194 AD - Biomedizinische NMR Forschungs GmbH am Max-Planck-Institut für biophysikalische Chemie, Göttingen, Germany. EP - 736 TI - Rapid isotropic diffusion mapping without susceptibility artifacts: whole brain studies using diffusion-weighted single-shot STEAM MR imaging. VL - 44 SP - 731 KW - distorsion-geometric KW - dti KW - sequence AU - Nolte, UG AU - Finsterbusch, J AU - Frahm, J PY - 2000/11// UR - http://view.ncbi.nlm.nih.gov/pubmed/11064408 ER -