The acquisition of skilled motor performance: fast and slow experience-driven changes in primary motor cortex. Export

@article{citeulike:853432, abstract = {Behavioral and neurophysiological studies suggest that skill learning can be mediated by discrete, experience-driven changes within specific neural representations subserving the performance of the trained task. We have shown that a few minutes of daily practice on a sequential finger opposition task induced large, incremental performance gains over a few weeks of training. These gains did not generalize to the contralateral hand nor to a matched sequence of identical component movements, suggesting that a lateralized representation of the learned sequence of movements evolved through practice. This interpretation was supported by functional MRI data showing that a more extensive representation of the trained sequence emerged in primary motor cortex after 3 weeks of training. The imaging data, however, also indicated important changes occurring in primary motor cortex during the initial scanning sessions, which we proposed may reflect the setting up of a task-specific motor processing routine. Here we provide behavioral and functional MRI data on experience-dependent changes induced by a limited amount of repetitions within the first imaging session. We show that this limited training experience can be sufficient to trigger performance gains that require time to become evident. We propose that skilled motor performance is acquired in several stages: "fast" learning, an initial, within-session improvement phase, followed by a period of consolidation of several hours duration, and then "slow" learning, consisting of delayed, incremental gains in performance emerging after continued practice. This time course may reflect basic mechanisms of neuronal plasticity in the adult brain that subserve the acquisition and retention of many different skills.}, address = {Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, 49 Convent Drive, Bethesda MD 20892, USA.}, author = {Karni, A. and Meyer, G. and Rey-Hipolito, C. and Jezzard, P. and Adams, M. M. and Turner, R. and Ungerleider, L. G.}, citeulike-article-id = {853432}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/9448252}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=9448252}, day = {3}, issn = {0027-8424}, journal = {Proc Natl Acad Sci U S A}, keywords = {fmri, learning, motor}, month = {February}, number = {3}, pages = {861--868}, posted-at = {2006-09-21 20:54:38}, priority = {2}, title = {The acquisition of skilled motor performance: fast and slow experience-driven changes in primary motor cortex.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/9448252}, volume = {95}, year = {1998} }

TY - JOUR ID - citeulike:853432 L3 - citeulike-article-id:853432 N2 - Behavioral and neurophysiological studies suggest that skill learning can be mediated by discrete, experience-driven changes within specific neural representations subserving the performance of the trained task. We have shown that a few minutes of daily practice on a sequential finger opposition task induced large, incremental performance gains over a few weeks of training. These gains did not generalize to the contralateral hand nor to a matched sequence of identical component movements, suggesting that a lateralized representation of the learned sequence of movements evolved through practice. This interpretation was supported by functional MRI data showing that a more extensive representation of the trained sequence emerged in primary motor cortex after 3 weeks of training. The imaging data, however, also indicated important changes occurring in primary motor cortex during the initial scanning sessions, which we proposed may reflect the setting up of a task-specific motor processing routine. Here we provide behavioral and functional MRI data on experience-dependent changes induced by a limited amount of repetitions within the first imaging session. We show that this limited training experience can be sufficient to trigger performance gains that require time to become evident. We propose that skilled motor performance is acquired in several stages: "fast" learning, an initial, within-session improvement phase, followed by a period of consolidation of several hours duration, and then "slow" learning, consisting of delayed, incremental gains in performance emerging after continued practice. This time course may reflect basic mechanisms of neuronal plasticity in the adult brain that subserve the acquisition and retention of many different skills. IS - 3 JF - Proc Natl Acad Sci U S A SN - 0027-8424 AD - Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, 49 Convent Drive, Bethesda MD 20892, USA. EP - 868 TI - The acquisition of skilled motor performance: fast and slow experience-driven changes in primary motor cortex. VL - 95 SP - 861 KW - fmri KW - learning KW - motor AU - Karni, A AU - Meyer, G AU - Rey-Hipolito, C AU - Jezzard, P AU - Adams, MM AU - Turner, R AU - Ungerleider, LG PY - 1998/02/03/ UR - http://view.ncbi.nlm.nih.gov/pubmed/9448252 ER -