Ultrasome: efficient aberration caller for copy number studies of ultra-high resolution. Export

@article{citeulike:4073369, abstract = {MOTIVATION: Multimillion-probe microarrays allow detection of gains and losses of chromosomal material at unprecedented resolution. However, the data generated by these arrays are several-fold larger than data from earlier platforms, creating a need for efficient analysis tools that scale robustly with data size. RESULTS: We developed a new aberration caller, Ultrasome, that delineates genomic changes-of-interest with dramatically improved efficiency. Ultrasome shows near-linear computational complexity and processes latest generation copy number arrays about 10,000 times faster than standard methods with preserved analytic accuracy.}, author = {Nilsson, Bj\"{o}rn and Johansson, Mikael and Al-Shahrour, Fatima and Carpenter, Anne E. and Ebert, Benjamin L.}, citeulike-article-id = {4073369}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/bioinformatics/btp091}, citeulike-linkout-1 = {http://bioinformatics.oxfordjournals.org/content/25/8/1078.abstract}, citeulike-linkout-2 = {http://bioinformatics.oxfordjournals.org/content/25/8/1078.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/19228802}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=19228802}, day = {15}, doi = {10.1093/bioinformatics/btp091}, issn = {1460-2059}, journal = {Bioinformatics (Oxford, England)}, keywords = {copy-number, segmentation, software}, month = {April}, number = {8}, pages = {1078--1079}, posted-at = {2009-11-02 17:27:22}, priority = {4}, title = {Ultrasome: efficient aberration caller for copy number studies of ultra-high resolution.}, url = {http://dx.doi.org/10.1093/bioinformatics/btp091}, volume = {25}, year = {2009} }

TY - JOUR ID - citeulike:4073369 L3 - citeulike-article-id:4073369 N2 - MOTIVATION: Multimillion-probe microarrays allow detection of gains and losses of chromosomal material at unprecedented resolution. However, the data generated by these arrays are several-fold larger than data from earlier platforms, creating a need for efficient analysis tools that scale robustly with data size. RESULTS: We developed a new aberration caller, Ultrasome, that delineates genomic changes-of-interest with dramatically improved efficiency. Ultrasome shows near-linear computational complexity and processes latest generation copy number arrays about 10,000 times faster than standard methods with preserved analytic accuracy. IS - 8 JF - Bioinformatics (Oxford, England) SN - 1460-2059 EP - 1079 TI - Ultrasome: efficient aberration caller for copy number studies of ultra-high resolution. VL - 25 SP - 1078 KW - copy-number KW - segmentation KW - software AU - Nilsson, Björn AU - Johansson, Mikael AU - Al-Shahrour, Fatima AU - Carpenter, Anne AU - Ebert, Benjamin PY - 2009/04/15/ UR - http://dx.doi.org/10.1093/bioinformatics/btp091 ER -