Noncoding RNAs and Gene Silencing Export

@article{citeulike:1123024, abstract = {Noncoding RNA has long been proposed to control gene expression via sequence-specific interactions with regulatory regions. Here, we review the role of noncoding RNA in heterochromatic silencing and in the silencing of transposable elements (TEs), unpaired DNA in meiosis, and developmentally excised DNA. The role of cotranscriptional processing by RNA interference and by other mechanisms is discussed, as well as parallels with RNA silencing in imprinting, paramutation, polycomb silencing, and X inactivation. Interactions with regulatory sequences may well occur, but at the RNA rather than at the DNA level.}, author = {Zaratiegui, Mikel and Irvine, Danielle V. and Martienssen, Robert A.}, citeulike-article-id = {1123024}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.cell.2007.02.016}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0092867407001894}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/17320512}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=17320512}, citeulike-linkout-4 = {http://www.sciencedirect.com/science/article/B6WSN-4N3XF1K-J/2/c8b688f31a9e2fee65eaed2c4d8e1fad}, day = {23}, doi = {10.1016/j.cell.2007.02.016}, journal = {Cell}, keywords = {review, silencing, smrna}, month = {February}, number = {4}, pages = {763--776}, posted-at = {2008-11-21 21:51:44}, priority = {2}, title = {Noncoding RNAs and Gene Silencing}, url = {http://dx.doi.org/10.1016/j.cell.2007.02.016}, volume = {128}, year = {2007} }

TY - JOUR ID - citeulike:1123024 L3 - citeulike-article-id:1123024 N2 - Noncoding RNA has long been proposed to control gene expression via sequence-specific interactions with regulatory regions. Here, we review the role of noncoding RNA in heterochromatic silencing and in the silencing of transposable elements (TEs), unpaired DNA in meiosis, and developmentally excised DNA. The role of cotranscriptional processing by RNA interference and by other mechanisms is discussed, as well as parallels with RNA silencing in imprinting, paramutation, polycomb silencing, and X inactivation. Interactions with regulatory sequences may well occur, but at the RNA rather than at the DNA level. IS - 4 JF - Cell EP - 776 TI - Noncoding RNAs and Gene Silencing VL - 128 SP - 763 KW - review KW - silencing KW - smrna AU - Zaratiegui, Mikel AU - Irvine, Danielle AU - Martienssen, Robert PY - 2007/02/23/ UR - http://dx.doi.org/10.1016/j.cell.2007.02.016 ER -