Maintenance of heterochromatin by RNA interference of tandem repeats. Export

@article{citeulike:140152, abstract = {Tandem repeats are prone to epigenetic silencing regulated by RNA interference. This may be because siRNAs from tandem array transcripts are regenerated by RNA-dependent RNA polymerase (RdRP) and Dicer, but siRNAs from single-copy sequences are exhausted by sequential use of downstream primers by RdRP. This could account for the formation of heterochromatin from tandem repeats.}, address = {Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA. martiens@cshl.org}, author = {Martienssen, R. A.}, citeulike-article-id = {140152}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/ng1252}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/ng1252}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/14593407}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=14593407}, doi = {10.1038/ng1252}, issn = {1061-4036}, journal = {Nat Genet}, keywords = {methylation, silencing, smrna, tandem\_repeats}, month = {November}, number = {3}, pages = {213--214}, posted-at = {2008-11-22 16:40:59}, priority = {2}, title = {Maintenance of heterochromatin by RNA interference of tandem repeats.}, url = {http://dx.doi.org/10.1038/ng1252}, volume = {35}, year = {2003} }

TY - JOUR ID - citeulike:140152 L3 - citeulike-article-id:140152 N2 - Tandem repeats are prone to epigenetic silencing regulated by RNA interference. This may be because siRNAs from tandem array transcripts are regenerated by RNA-dependent RNA polymerase (RdRP) and Dicer, but siRNAs from single-copy sequences are exhausted by sequential use of downstream primers by RdRP. This could account for the formation of heterochromatin from tandem repeats. IS - 3 JF - Nat Genet SN - 1061-4036 AD - Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA. martiens@cshl.org EP - 214 TI - Maintenance of heterochromatin by RNA interference of tandem repeats. VL - 35 SP - 213 KW - methylation KW - silencing KW - smrna KW - tandem_repeats AU - Martienssen, RA PY - 2003/11// UR - http://dx.doi.org/10.1038/ng1252 ER -