Attentional integration between anatomically distinct stimulus representations in early visual cortex. Export

@article{citeulike:3049807, abstract = {Vision often requires attending to, and integrating information from, distant parts of the visual field. However, the neural basis for such long-range integration is not clearly understood. Here, we demonstrate a specific neural signature of attentional integration between stimuli in different parts of the visual field. Using functional MRI, we found that a task requiring the integration of information between two attended but spatially separated stimuli actively modulated the degree of functional integration (in terms of effective connectivity) between their retinotopic representations in visual cortical areas V1, V2, and V4. Spatial attention enhanced long-distance coupling between distinct neuronal populations that represented the attended visual stimuli, even at the earliest stages of cortical processing. In contrast, unattended stimulus representations were decoupled both from attended representations and particularly strongly from each other. Furthermore, enhanced functional integration between cortical representations was associated with enhanced behavioral performance. Attention may thus serve to "bind" together cortical loci at multiple levels of the visual hierarchy that are commonly involved in processing attended stimuli, promoting integration between otherwise functionally isolated cortical loci.}, address = {Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, United Kingdom. haynes@fil.ion.ucl.ac.uk}, author = {Haynes, J. D. and Tregellas, J. and Rees, G.}, citeulike-article-id = {3049807}, citeulike-linkout-0 = {http://dx.doi.org/10.1073/pnas.0501684102}, citeulike-linkout-1 = {http://www.pnas.org/content/102/41/14925.abstract}, citeulike-linkout-2 = {http://www.pnas.org/content/102/41/14925.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/16192359}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=16192359}, day = {11}, doi = {10.1073/pnas.0501684102}, issn = {0027-8424}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, keywords = {attention, fmri, lateral-interactions}, month = {October}, number = {41}, pages = {14925--14930}, posted-at = {2009-07-27 21:34:07}, priority = {0}, title = {Attentional integration between anatomically distinct stimulus representations in early visual cortex.}, url = {http://dx.doi.org/10.1073/pnas.0501684102}, volume = {102}, year = {2005} }

TY - JOUR ID - citeulike:3049807 L3 - citeulike-article-id:3049807 N2 - Vision often requires attending to, and integrating information from, distant parts of the visual field. However, the neural basis for such long-range integration is not clearly understood. Here, we demonstrate a specific neural signature of attentional integration between stimuli in different parts of the visual field. Using functional MRI, we found that a task requiring the integration of information between two attended but spatially separated stimuli actively modulated the degree of functional integration (in terms of effective connectivity) between their retinotopic representations in visual cortical areas V1, V2, and V4. Spatial attention enhanced long-distance coupling between distinct neuronal populations that represented the attended visual stimuli, even at the earliest stages of cortical processing. In contrast, unattended stimulus representations were decoupled both from attended representations and particularly strongly from each other. Furthermore, enhanced functional integration between cortical representations was associated with enhanced behavioral performance. Attention may thus serve to "bind" together cortical loci at multiple levels of the visual hierarchy that are commonly involved in processing attended stimuli, promoting integration between otherwise functionally isolated cortical loci. IS - 41 JF - Proceedings of the National Academy of Sciences of the United States of America SN - 0027-8424 AD - Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, United Kingdom. haynes@fil.ion.ucl.ac.uk EP - 14930 TI - Attentional integration between anatomically distinct stimulus representations in early visual cortex. VL - 102 SP - 14925 KW - attention KW - fmri KW - lateral-interactions AU - Haynes, JD AU - Tregellas, J AU - Rees, G PY - 2005/10/11/ UR - http://dx.doi.org/10.1073/pnas.0501684102 ER -