Bacterial Programmed Cell Death and Multicellular Behavior in Bacteria Export

@article{citeulike:914130, abstract = {Traditionally, programmed cell death (PCD) is associated with eukaryotic multicellular organisms. However, recently, PCD systems have also been observed in bacteria. Here we review recent research on two kinds of genetic programs that promote bacterial cell death. The first is mediated by mazEF, a toxin\&\#8211;antitoxin module found in the chromosomes of many kinds of bacteria, and mainly studied in Escherichia coli. The second program is found in Bacillus subtilis, in which the skf and sdp operons mediate the death of a subpopulation of sporulating bacterial cells. We relate these two bacterial PCD systems to the ways in which bacterial populations resemble multicellular organisms.}, author = {Engelberg-Kulka, Hanna and Amitai, Shahar and Kolodkin-Gal, Ilana and Hazan, Ronen}, citeulike-article-id = {914130}, citeulike-linkout-0 = {http://dx.doi.org/10.1371/journal.pgen.0020135}, day = {1}, doi = {10.1371/journal.pgen.0020135}, journal = {PLoS Genetics}, keywords = {bacteria, biofilm, microbial-community, microbial-interaction}, month = {October}, number = {10}, pages = {e135+}, posted-at = {2006-10-27 01:48:12}, priority = {2}, title = {Bacterial Programmed Cell Death and Multicellular Behavior in Bacteria}, url = {http://dx.doi.org/10.1371/journal.pgen.0020135}, volume = {2}, year = {2006} }

TY - JOUR ID - citeulike:914130 L3 - citeulike-article-id:914130 N2 - Traditionally, programmed cell death (PCD) is associated with eukaryotic multicellular organisms. However, recently, PCD systems have also been observed in bacteria. Here we review recent research on two kinds of genetic programs that promote bacterial cell death. The first is mediated by mazEF, a toxin–antitoxin module found in the chromosomes of many kinds of bacteria, and mainly studied in Escherichia coli. The second program is found in Bacillus subtilis, in which the skf and sdp operons mediate the death of a subpopulation of sporulating bacterial cells. We relate these two bacterial PCD systems to the ways in which bacterial populations resemble multicellular organisms. IS - 10 JF - PLoS Genetics TI - Bacterial Programmed Cell Death and Multicellular Behavior in Bacteria VL - 2 SP - e135 KW - bacteria KW - biofilm KW - microbial-community KW - microbial-interaction AU - Engelberg-Kulka, Hanna AU - Amitai, Shahar AU - Kolodkin-Gal, Ilana AU - Hazan, Ronen PY - 2006/10/01/ UR - http://dx.doi.org/10.1371/journal.pgen.0020135 ER -