Cortico-basal ganglia-cortical circuitry in Parkinson's disease reconsidered. Export

@article{citeulike:3253464, abstract = {The classical model of the cortico-basal ganglia-cortical circuit, with its indirect and direct pathways, was developed to explain the phenomenon of hypokinesia in Parkinson's disease (PD). The model has undergone refinement, but the emphasis on the basal ganglia side of the equation (dopamine deficiency in the dorsal striatum) remains. Here, a revised version of the basic model incorporates key non-dopaminergic connectivities known to become affected in the course of PD and, thus, the cortico-basal ganglia-cortical circuit appears within the context of the larger pathological process. The central roles of the corticostriatal projection, corticosubthalamic projection, and lower brainstem nuclei are emphasized.}, author = {Braak, Heiko and Del Tredici, Kelly}, citeulike-article-id = {3253464}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.expneurol.2008.04.001}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18501351}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18501351}, citeulike-linkout-3 = {http://www.sciencedirect.com/science/article/B6WFG-4S92TR3-2/2/e340c86c87839d806db11e42150d1813}, doi = {10.1016/j.expneurol.2008.04.001}, issn = {1090-2430}, journal = {Experimental neurology}, keywords = {basal\_ganglia, circuit, hyperdirect, lewy\_body\_pathology}, month = {July}, number = {1}, pages = {226--229}, posted-at = {2009-10-19 10:28:35}, priority = {2}, title = {Cortico-basal ganglia-cortical circuitry in Parkinson's disease reconsidered.}, url = {http://dx.doi.org/10.1016/j.expneurol.2008.04.001}, volume = {212}, year = {2008} }

TY - JOUR ID - citeulike:3253464 L3 - citeulike-article-id:3253464 N2 - The classical model of the cortico-basal ganglia-cortical circuit, with its indirect and direct pathways, was developed to explain the phenomenon of hypokinesia in Parkinson's disease (PD). The model has undergone refinement, but the emphasis on the basal ganglia side of the equation (dopamine deficiency in the dorsal striatum) remains. Here, a revised version of the basic model incorporates key non-dopaminergic connectivities known to become affected in the course of PD and, thus, the cortico-basal ganglia-cortical circuit appears within the context of the larger pathological process. The central roles of the corticostriatal projection, corticosubthalamic projection, and lower brainstem nuclei are emphasized. IS - 1 JF - Experimental neurology SN - 1090-2430 EP - 229 TI - Cortico-basal ganglia-cortical circuitry in Parkinson's disease reconsidered. VL - 212 SP - 226 KW - basal_ganglia KW - circuit KW - hyperdirect KW - lewy_body_pathology AU - Braak, Heiko AU - Del Tredici, Kelly PY - 2008/07// UR - http://dx.doi.org/10.1016/j.expneurol.2008.04.001 ER -