Communicating with Hedgehogs Export

@article{citeulike:108885, abstract = {Signalling by secreted Hedgehog (Hh) proteins is important for the development of many tissues and organs. Damage to components of the Hh signal-transduction pathway can lead to birth defects and cancer. The Hh proteins are distributed in tissues in a gradient, and cells respond to different thresholds of Hh with distinct responses. The cellular machinery that is responsible for the unique molecular mechanisms of Hh signal transduction has been largely conserved during metazoan evolution.}, author = {Hooper, J. E. and Scott, M. P.}, citeulike-article-id = {108885}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nrm1612}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/15803137}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=15803137}, day = {01}, doi = {10.1038/nrm1612}, issn = {1471-0072}, journal = {Nature Reviews Molecular Cell Biology}, keywords = {hedgehog, review}, month = {April}, number = {4}, pages = {306--317}, posted-at = {2005-05-14 20:28:32}, priority = {5}, publisher = {Nature Publishing Group}, title = {Communicating with Hedgehogs}, url = {http://dx.doi.org/10.1038/nrm1612}, volume = {6}, year = {2005} }

TY - JOUR ID - citeulike:108885 L3 - citeulike-article-id:108885 N2 - Signalling by secreted Hedgehog (Hh) proteins is important for the development of many tissues and organs. Damage to components of the Hh signal-transduction pathway can lead to birth defects and cancer. The Hh proteins are distributed in tissues in a gradient, and cells respond to different thresholds of Hh with distinct responses. The cellular machinery that is responsible for the unique molecular mechanisms of Hh signal transduction has been largely conserved during metazoan evolution. IS - 4 JF - Nature Reviews Molecular Cell Biology SN - 1471-0072 EP - 317 TI - Communicating with Hedgehogs PB - Nature Publishing Group VL - 6 SP - 306 KW - hedgehog KW - review AU - Hooper, JE AU - Scott, MP PY - 2005/04/01/ UR - http://dx.doi.org/10.1038/nrm1612 ER -