Low and Very Low Birth Weight in Infants Conceived with Use of Assisted Reproductive Technology

Infants who have low birth weight, either because of early delivery or because of fetal growth restriction, are at increased risk for short- and long-term disabilities and death.1,2 The use of assisted reproductive technology is an important contributor to the rate of low birth weight in the United States because it is associated with a higher rate of multiple birth,3,4 which, in turn, is associated with low birth weight.5 By 1997, the use of assisted reproductive technology accounted for more than 40 percent of triplets born in the United States.4 In addition, studies have suggested that there is . . .