Shape complementarity at protein/protein interfaces. Export

@article{citeulike:1540356, abstract = {A new statistic Sc, which has a number of advantages over other measures of packing, is used to examine the shape complementarity of protein/protein interfaces selected from the Brookhaven Protein Data Bank. It is shown using Sc that antibody/antigen interfaces as a whole exhibit poorer shape complementarity than is observed in other systems involving protein/protein interactions. This result can be understood in terms of the fundamentally different evolutionary history of particular antibody/antigen associations compared to other systems considered, and in terms of the differing chemical natures of the interfaces.}, address = {Biomolecular Research Institute, Parkville, Victoria, Australia.}, author = {Lawrence, M. C. and Colman, P. M.}, citeulike-article-id = {1540356}, citeulike-linkout-0 = {http://dx.doi.org/10.1006/jmbi.1993.1648}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/8263940}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=8263940}, day = {20}, doi = {10.1006/jmbi.1993.1648}, issn = {0022-2836}, journal = {Journal of molecular biology}, keywords = {ccp4, docking, protein\_docking, structural\_bioinformatics, xtal\_methods, xtal\_software}, month = {December}, number = {4}, pages = {946--950}, posted-at = {2007-08-07 13:35:44}, priority = {2}, title = {Shape complementarity at protein/protein interfaces.}, url = {http://dx.doi.org/10.1006/jmbi.1993.1648}, volume = {234}, year = {1993} }

TY - JOUR ID - citeulike:1540356 L3 - citeulike-article-id:1540356 N2 - A new statistic Sc, which has a number of advantages over other measures of packing, is used to examine the shape complementarity of protein/protein interfaces selected from the Brookhaven Protein Data Bank. It is shown using Sc that antibody/antigen interfaces as a whole exhibit poorer shape complementarity than is observed in other systems involving protein/protein interactions. This result can be understood in terms of the fundamentally different evolutionary history of particular antibody/antigen associations compared to other systems considered, and in terms of the differing chemical natures of the interfaces. IS - 4 JF - Journal of molecular biology SN - 0022-2836 AD - Biomolecular Research Institute, Parkville, Victoria, Australia. EP - 950 TI - Shape complementarity at protein/protein interfaces. VL - 234 SP - 946 KW - ccp4 KW - docking KW - protein_docking KW - structural_bioinformatics KW - xtal_methods KW - xtal_software AU - Lawrence, MC AU - Colman, PM PY - 1993/12/20/ UR - http://dx.doi.org/10.1006/jmbi.1993.1648 ER -