MIPS: analysis and annotation of genome information in 2007.

@article{citeulike:2782605, abstract = {The Munich Information Center for Protein Sequences (MIPS-GSF, Neuherberg, Germany) combines automatic processing of large amounts of sequences with manual annotation of selected model genomes. Due to the massive growth of the available data, the depth of annotation varies widely between independent databases. Also, the criteria for the transfer of information from known to orthologous sequences are diverse. To cope with the task of global in-depth genome annotation has become unfeasible. Therefore, our efforts are dedicated to three levels of annotation: (i) the curation of selected genomes, in particular from fungal and plant taxa (e.g. CYGD, MNCDB, MatDB), (ii) the comprehensive, consistent, automatic annotation employing exhaustive methods for the computation of sequence similarities and sequence-related attributes as well as the classification of individual sequences (SIMAP, PEDANT and FunCat) and (iii) the compilation of manually curated databases for protein interactions based on scrutinized information from the literature to serve as an accepted set of reliable annotated interaction data (MPACT, MPPI, CORUM). All databases and tools described as well as the detailed descriptions of our projects can be accessed through the MIPS web server (http://mips.gsf.de).}, address = {Institute for Bioinformatics (MIPS), German Research Center for Environmental Health, Ingolstaedter Landstrasse 1, D-85764 Neuherberg, Germany.}, author = {Mewes, H. W. and Dietmann, S. and Frishman, D. and Gregory, R. and Mannhaupt, G. and Mayer, K. F. and M\"{u}nsterk\"{o}tter, M. and Ruepp, A. and Spannagl, M. and St\"{u}mpflen, V. and Rattei, T. }, citeulike-article-id = {2782605}, issn = {1362-4962}, journal = {Nucleic acids research}, keywords = {database}, month = {January}, number = {Database issue}, posted-at = {2008-05-10 09:57:42}, priority = {2}, title = {MIPS: analysis and annotation of genome information in 2007.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/18158298}, volume = {36}, year = {2008} }

TY - JOUR ID - citeulike:2782605 L3 - citeulike-article-id:2782605 TI - MIPS: analysis and annotation of genome information in 2007. JF - Nucleic acids research VL - 36 IS - Database issue AD - Institute for Bioinformatics (MIPS), German Research Center for Environmental Health, Ingolstaedter Landstrasse 1, D-85764 Neuherberg, Germany. SN - 1362-4962 N2 - The Munich Information Center for Protein Sequences (MIPS-GSF, Neuherberg, Germany) combines automatic processing of large amounts of sequences with manual annotation of selected model genomes. Due to the massive growth of the available data, the depth of annotation varies widely between independent databases. Also, the criteria for the transfer of information from known to orthologous sequences are diverse. To cope with the task of global in-depth genome annotation has become unfeasible. Therefore, our efforts are dedicated to three levels of annotation: (i) the curation of selected genomes, in particular from fungal and plant taxa (e.g. CYGD, MNCDB, MatDB), (ii) the comprehensive, consistent, automatic annotation employing exhaustive methods for the computation of sequence similarities and sequence-related attributes as well as the classification of individual sequences (SIMAP, PEDANT and FunCat) and (iii) the compilation of manually curated databases for protein interactions based on scrutinized information from the literature to serve as an accepted set of reliable annotated interaction data (MPACT, MPPI, CORUM). All databases and tools described as well as the detailed descriptions of our projects can be accessed through the MIPS web server (http://mips.gsf.de). KW - database AU - Mewes, HW AU - Dietmann, S AU - Frishman, D AU - Gregory, R AU - Mannhaupt, G AU - Mayer, KF AU - Münsterkötter, M AU - Ruepp, A AU - Spannagl, M AU - Stümpflen, V AU - Rattei, T PY - 2008/01// UR - http://view.ncbi.nlm.nih.gov/pubmed/18158298 ER -