Use and misuse of the gene ontology annotations.

by: Seung Yon Rhee, Valerie Wood, Kara Dolinski, Sorin Draghici

Nature reviews. Genetics (13 May 2008)

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Abstract

The Gene Ontology (GO) project is a collaboration among model organism databases to describe gene products from all organisms using a consistent and computable language. GO produces sets of explicitly defined, structured vocabularies that describe biological processes, molecular functions and cellular components of gene products in both a computer- and human-readable manner. Here we describe key aspects of GO, which, when overlooked, can cause erroneous results, and address how these pitfalls can be avoided.

@article{citeulike:2800782, abstract = {The Gene Ontology (GO) project is a collaboration among model organism databases to describe gene products from all organisms using a consistent and computable language. GO produces sets of explicitly defined, structured vocabularies that describe biological processes, molecular functions and cellular components of gene products in both a computer- and human-readable manner. Here we describe key aspects of GO, which, when overlooked, can cause erroneous results, and address how these pitfalls can be avoided.}, address = {Carnegie Institution for Science, Department of Plant Biology, 260 Panama Street, Stanford, California 94305, USA.}, author = {Yon Rhee, Seung and Wood, Valerie and Dolinski, Kara and Draghici, Sorin }, citeulike-article-id = {2800782}, doi = {10.1038/nrg2363}, issn = {1471-0064}, journal = {Nature reviews. Genetics}, keywords = {ontology}, month = {May}, posted-at = {2008-05-16 05:31:42}, priority = {2}, title = {Use and misuse of the gene ontology annotations.}, url = {http://dx.doi.org/10.1038/nrg2363}, year = {2008} }

RIS record

TY - JOUR ID - citeulike:2800782 L3 - citeulike-article-id:2800782 TI - Use and misuse of the gene ontology annotations. JF - Nature reviews. Genetics AD - Carnegie Institution for Science, Department of Plant Biology, 260 Panama Street, Stanford, California 94305, USA. SN - 1471-0064 N2 - The Gene Ontology (GO) project is a collaboration among model organism databases to describe gene products from all organisms using a consistent and computable language. GO produces sets of explicitly defined, structured vocabularies that describe biological processes, molecular functions and cellular components of gene products in both a computer- and human-readable manner. Here we describe key aspects of GO, which, when overlooked, can cause erroneous results, and address how these pitfalls can be avoided. KW - ontology AU - Yon Rhee, Seung AU - Wood, Valerie AU - Dolinski, Kara AU - Draghici, Sorin PY - 2008/05/13/ UR - http://dx.doi.org/10.1038/nrg2363 ER -

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