The anticancer effects of vitamin K. Export

@article{citeulike:608374, abstract = {Vitamin K, an essential nutrient often associated with the clotting cascade, has been the focus of considerable research demonstrating an anticancer potential. Much of this research has focused on vitamin K3, although vitamins K2 and K1 have also been shown to have anticancer effects. Early studies of vitamin K3 employed an oxidative model to explain the anticancer effects seen in both in vitro and in vivo studies; however, this model does not adequately address the action of vitamins K1 and K2. Recent research has demonstrated the anticancer action of vitamin K may act at the level of tyrosine kinases and phosphatases, modulating various transcription factors such as Myc and Fos. Tyrosine kinases associated with cyclins have also been shown to be affected by vitamin K, which can lead to cell cycle arrest and cell death.}, address = {Coordinator of Oncology, Bastyr University, Kenmore, Washington, USA. davisl@seanet.com}, author = {Lamson, Davis W. and Plaza, Steven M.}, citeulike-article-id = {608374}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/12946240}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=12946240}, issn = {1089-5159}, journal = {Alternative medicine review : a journal of clinical therapeutic}, keywords = {anticancer, review, vitamink}, month = {August}, number = {3}, pages = {303--318}, posted-at = {2006-05-01 03:25:01}, priority = {0}, title = {The anticancer effects of vitamin K.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/12946240}, volume = {8}, year = {2003} }

TY - JOUR ID - citeulike:608374 L3 - citeulike-article-id:608374 N2 - Vitamin K, an essential nutrient often associated with the clotting cascade, has been the focus of considerable research demonstrating an anticancer potential. Much of this research has focused on vitamin K3, although vitamins K2 and K1 have also been shown to have anticancer effects. Early studies of vitamin K3 employed an oxidative model to explain the anticancer effects seen in both in vitro and in vivo studies; however, this model does not adequately address the action of vitamins K1 and K2. Recent research has demonstrated the anticancer action of vitamin K may act at the level of tyrosine kinases and phosphatases, modulating various transcription factors such as Myc and Fos. Tyrosine kinases associated with cyclins have also been shown to be affected by vitamin K, which can lead to cell cycle arrest and cell death. IS - 3 JF - Alternative medicine review : a journal of clinical therapeutic SN - 1089-5159 AD - Coordinator of Oncology, Bastyr University, Kenmore, Washington, USA. davisl@seanet.com EP - 318 TI - The anticancer effects of vitamin K. VL - 8 SP - 303 KW - anticancer KW - review KW - vitamink AU - Lamson, Davis AU - Plaza, Steven PY - 2003/08// UR - http://view.ncbi.nlm.nih.gov/pubmed/12946240 ER -