A Test of the Master Gene Hypothesis for Interspersed Repetitive DNA Sequences Export

@article{citeulike:460149, abstract = {Many families of interspersed repetitive DNA elements, including human Alu and LINE (Long Interspersed Element) elements, have been proposed to have accumulated through repeated copying from a single source locus: the "master gene." The extent to which a master gene model is applicable has implications for the origin, evolution, and function of such sequences. One repetitive element family for which a convincing case for a master gene has been made is the rodent ID (identifier) elements. Here we devise a new test of the master gene model and use it to show that mouse ID element sequences are not compatible with a strict master gene model. We suggest that a single master gene is rarely, if ever, likely to be responsible for the accumulation of any repeat family.}, author = {Johnson, Louise J. and Brookfield, John F.}, citeulike-article-id = {460149}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/molbev/msj034}, citeulike-linkout-1 = {http://mbe.oxfordjournals.org/cgi/content/abstract/23/2/235}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/16221895}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=16221895}, day = {1}, doi = {10.1093/molbev/msj034}, journal = {Mol Biol Evol}, keywords = {06, dna, express, gene\_, mgh}, month = {February}, number = {2}, pages = {235--239}, posted-at = {2009-04-09 08:33:01}, priority = {2}, title = {A Test of the Master Gene Hypothesis for Interspersed Repetitive DNA Sequences}, url = {http://dx.doi.org/10.1093/molbev/msj034}, volume = {23}, year = {2006} }

TY - JOUR ID - citeulike:460149 L3 - citeulike-article-id:460149 N2 - Many families of interspersed repetitive DNA elements, including human Alu and LINE (Long Interspersed Element) elements, have been proposed to have accumulated through repeated copying from a single source locus: the "master gene." The extent to which a master gene model is applicable has implications for the origin, evolution, and function of such sequences. One repetitive element family for which a convincing case for a master gene has been made is the rodent ID (identifier) elements. Here we devise a new test of the master gene model and use it to show that mouse ID element sequences are not compatible with a strict master gene model. We suggest that a single master gene is rarely, if ever, likely to be responsible for the accumulation of any repeat family. IS - 2 JF - Mol Biol Evol EP - 239 TI - A Test of the Master Gene Hypothesis for Interspersed Repetitive DNA Sequences VL - 23 SP - 235 KW - 06 KW - dna KW - express KW - gene_ KW - mgh AU - Johnson, Louise AU - Brookfield, John PY - 2006/02/01/ UR - http://dx.doi.org/10.1093/molbev/msj034 ER -