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Opinion: The cortex as a central pattern generator Export

Nature Reviews Neuroscience, Vol. 6, No. 6. (01 June 2005), pp. 477-483.

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  • suggests functional equivalence between vertebrate spinal cord/brainstem central pattern generator (CPG) circuits and neocortex
  • key idea is the production of meaningful patterns of activity in the absence of sensory input
  • outlines anatomical ('excitatory core', recurrent excitation, precise connections), biophysical (ion channels, membrane properties, oscillation and synchrony), dynamic (attractor states), and neuromodulatory similarities between these two systems
  • argues that neocortex may represent a particularly plastic type of CPG
klouie (public note) - 2005-06-15 22:16:40

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