The Role of Human Orbitofrontal Cortex in Value Comparison for Incommensurable Objects Export

@article{citeulike:5848703, abstract = {The human orbitofrontal cortex is strongly implicated in appetitive valuation. Whether its role extends to support comparative valuation necessary to explain probabilistic choice patterns for incommensurable goods is unknown. Using a binary choice paradigm, we derived the subjective values of different bundles of goods, under conditions of both gain and loss. We demonstrate that orbitofrontal activation reflects the difference in subjective value between available options, an effect evident across valuation for both gains and losses. In contrast, activation in dorsal striatum and supplementary motor areas reflects subjects' choice probabilities. These findings indicate that orbitofrontal cortex plays a pivotal role in valuation for incommensurable goods, a critical component process in human decision making. 10.1523/JNEUROSCI.0717-09.2009}, author = {FitzGerald, Thomas H. B. and Seymour, Ben and Dolan, Raymond J.}, citeulike-article-id = {5848703}, citeulike-linkout-0 = {http://dx.doi.org/10.1523/JNEUROSCI.0717-09.2009}, citeulike-linkout-1 = {http://www.jneurosci.org/content/29/26/8388.abstract}, citeulike-linkout-2 = {http://www.jneurosci.org/content/29/26/8388.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/19571129}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=19571129}, day = {1}, doi = {10.1523/JNEUROSCI.0717-09.2009}, journal = {J. Neurosci.}, keywords = {fmri, neuroeconomy, ofc, valuation}, month = {July}, number = {26}, pages = {8388--8395}, posted-at = {2009-09-29 09:30:03}, priority = {2}, title = {The Role of Human Orbitofrontal Cortex in Value Comparison for Incommensurable Objects}, url = {http://dx.doi.org/10.1523/JNEUROSCI.0717-09.2009}, volume = {29}, year = {2009} }

TY - JOUR ID - citeulike:5848703 L3 - citeulike-article-id:5848703 N2 - The human orbitofrontal cortex is strongly implicated in appetitive valuation. Whether its role extends to support comparative valuation necessary to explain probabilistic choice patterns for incommensurable goods is unknown. Using a binary choice paradigm, we derived the subjective values of different bundles of goods, under conditions of both gain and loss. We demonstrate that orbitofrontal activation reflects the difference in subjective value between available options, an effect evident across valuation for both gains and losses. In contrast, activation in dorsal striatum and supplementary motor areas reflects subjects' choice probabilities. These findings indicate that orbitofrontal cortex plays a pivotal role in valuation for incommensurable goods, a critical component process in human decision making. 10.1523/JNEUROSCI.0717-09.2009 IS - 26 JF - J. Neurosci. EP - 8395 TI - The Role of Human Orbitofrontal Cortex in Value Comparison for Incommensurable Objects VL - 29 SP - 8388 KW - fmri KW - neuroeconomy KW - ofc KW - valuation AU - FitzGerald, Thomas AU - Seymour, Ben AU - Dolan, Raymond PY - 2009/07/01/ UR - http://dx.doi.org/10.1523/JNEUROSCI.0717-09.2009 ER -