Entropy in protein folding and in protein—protein interactions Export

@article{citeulike:5154340, abstract = {The reduction of conformational entropy is a major barrier that has to be overcome in protein folding and binding. Changes in solvent entropy are also a major factor. Recent advances include clarification of the fundamental issues concerning the separation of entropy into components, the treatment of association entropy in binding, and the role of size and shape effects in solvation entropy. Advances in the application of entropy calculations include an emerging consensus for estimates of backbone and sidechain entropy loss in protein folding via use of numerically intensive methods for sampling, and use of the expanding protein-structure database.}, author = {Brady, G.}, citeulike-article-id = {5154340}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/S0959-440X(97)80028-0}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0959-440X(97)80028-0}, doi = {10.1016/S0959-440X(97)80028-0}, issn = {0959440X}, journal = {Current Opinion in Structural Biology}, keywords = {conformational\_entropy, entropy, estimates, protein\_folding, protein\_protein\_interactions, protein\_structure\_database}, month = {April}, number = {2}, pages = {215--221}, posted-at = {2009-10-06 13:04:04}, priority = {4}, title = {Entropy in protein folding and in protein—protein interactions}, url = {http://dx.doi.org/10.1016/S0959-440X(97)80028-0}, volume = {7}, year = {1997} }

TY - JOUR ID - citeulike:5154340 L3 - citeulike-article-id:5154340 N2 - The reduction of conformational entropy is a major barrier that has to be overcome in protein folding and binding. Changes in solvent entropy are also a major factor. Recent advances include clarification of the fundamental issues concerning the separation of entropy into components, the treatment of association entropy in binding, and the role of size and shape effects in solvation entropy. Advances in the application of entropy calculations include an emerging consensus for estimates of backbone and sidechain entropy loss in protein folding via use of numerically intensive methods for sampling, and use of the expanding protein-structure database. IS - 2 JF - Current Opinion in Structural Biology SN - 0959440X EP - 221 TI - Entropy in protein folding and in protein—protein interactions VL - 7 SP - 215 KW - conformational_entropy KW - entropy KW - estimates KW - protein_folding KW - protein_protein_interactions KW - protein_structure_database AU - Brady, G PY - 1997/04// UR - http://dx.doi.org/10.1016/S0959-440X(97)80028-0 ER -