Label-free optical biosensing with slot-waveguides Export

@article{barrios08:708, abstract = {We demonstrate label-free molecule detection by using an integrated biosensor based on a Si 3 N 4 /SiO 2 slot-waveguide microring resonator. Bovine serum albumin (BSA) and anti-BSA molecular binding events on the sensor surface are monitored through the measurement of resonant wavelength shifts with varying biomolecule concentrations. The biosensor exhibited sensitivities of 1.8 and 3.2 nm/(ng/mm 2 ) for the detection of anti-BSA and BSA, respectively. The estimated detection limits are 28 and 16 pg/mm 2 for anti-BSA and BSA, respectively, limited by wavelength resolution.}, author = {Barrios, Carlos A. and Ba\~{n}uls, Mar\'{i}a J. and Gonz\'{a}lez-Pedro, Victoria and Gylfason, Kristinn B. and S\'{a}nchez, Benito and Griol, Amadeu and Maquieira, A. and Sohlstr\"{o}m, H. and Holgado, M. and Casquel, R.}, citeulike-article-id = {2623376}, citeulike-linkout-0 = {http://www.opticsinfobase.org/abstract.cfm?id=156931}, journal = {Opt. Lett.}, keywords = {biosensor, experiment, hardcopy, kth\_papers, mst\_papers, own\_paper, protein, resonant\_sensor, ring\_resonator, sabio, sabio\_group\_papers, silicon\_nitride, silicon\_oxide, slot\_waveguide}, month = {April}, number = {7}, pages = {708--710}, posted-at = {2008-04-02 14:27:08}, priority = {0}, publisher = {OSA}, title = {Label-free optical biosensing with slot-waveguides}, url = {http://www.opticsinfobase.org/abstract.cfm?id=156931}, volume = {33}, year = {2008} }

TY - JOUR ID - barrios08:708 L3 - citeulike-article-id:2623376 N2 - We demonstrate label-free molecule detection by using an integrated biosensor based on a Si 3 N 4 /SiO 2 slot-waveguide microring resonator. Bovine serum albumin (BSA) and anti-BSA molecular binding events on the sensor surface are monitored through the measurement of resonant wavelength shifts with varying biomolecule concentrations. The biosensor exhibited sensitivities of 1.8 and 3.2 nm/(ng/mm 2 ) for the detection of anti-BSA and BSA, respectively. The estimated detection limits are 28 and 16 pg/mm 2 for anti-BSA and BSA, respectively, limited by wavelength resolution. IS - 7 JF - Opt. Lett. EP - 710 TI - Label-free optical biosensing with slot-waveguides PB - OSA VL - 33 SP - 708 KW - biosensor KW - experiment KW - hardcopy KW - kth_papers KW - mst_papers KW - own_paper KW - protein KW - resonant_sensor KW - ring_resonator KW - sabio KW - sabio_group_papers KW - silicon_nitride KW - silicon_oxide KW - slot_waveguide AU - Barrios, Carlos AU - Bañuls, María AU - González-Pedro, Victoria AU - Gylfason, Kristinn AU - Sánchez, Benito AU - Griol, Amadeu AU - Maquieira, A AU - Sohlström, H AU - Holgado, M AU - Casquel, R PY - 2008/04/01/ UR - http://www.opticsinfobase.org/abstract.cfm?id=156931 ER -