Six-Year Outcome of Cognitive Behavior Therapy for Prevention of Recurrent Depression Export

@article{citeulike:6084251, abstract = {OBJECTIVE: A paucity of studies use nonpharmacological strategies for preventing recurrence in depression. Cognitive behavior treatment of residual symptoms was found to yield a significantly lower relapse rate than clinical management in recurrent depression at a 2-year follow-up. The objective of this investigation was to provide a 6-year follow-up of cognitive behavior treatment versus clinical management. METHOD: Forty patients with recurrent major depression who had been successfully treated with antidepressant drugs were randomly assigned to either cognitive behavior treatment of residual symptoms (supplemented by lifestyle modification and well-being therapy) or clinical management. In both groups, antidepressant drugs were tapered and discontinued. A 6-year follow-up was undertaken. During this period, no antidepressant drugs were used unless a relapse ensued. RESULTS: Cognitive behavior treatment resulted in a significantly lower relapse rate (40\%) at a 6-year follow-up than did clinical management (90\%). When multiple recurrences were considered, the group that received cognitive behavior treatment had a significantly lower number of relapses in comparison with the clinical management group. CONCLUSIONS: The results suggest that the sequential use of cognitive behavior treatment after pharmacotherapy may improve the long-term outcome in recurrent depression. A significant proportion of patients with recurrent depression might be able to withdraw from medication successfully and to stay well for at least 6 years with a focused course of psychotherapy. 10.1176/appi.ajp.161.10.1872}, author = {Fava, Giovanni A. and Ruini, Chiara and Rafanelli, Chiara and Finos, Livio and Conti, Sandra and Grandi, Silvana}, citeulike-article-id = {6084251}, citeulike-linkout-0 = {http://dx.doi.org/10.1176/appi.ajp.161.10.1872}, citeulike-linkout-1 = {http://ajp.psychiatryonline.org/content/161/10/1872.abstract}, citeulike-linkout-2 = {http://ajp.psychiatryonline.org/content/161/10/1872.full.pdf}, citeulike-linkout-3 = {http://ajp.psychiatryonline.org/cgi/content/abstract/161/10/1872}, citeulike-linkout-4 = {http://view.ncbi.nlm.nih.gov/pubmed/15465985}, citeulike-linkout-5 = {http://www.hubmed.org/display.cgi?uids=15465985}, day = {1}, doi = {10.1176/appi.ajp.161.10.1872}, journal = {Am J Psychiatry}, keywords = {cbt, depression, relapse}, month = {October}, number = {10}, pages = {1872--1876}, posted-at = {2009-11-08 14:36:08}, priority = {0}, title = {Six-Year Outcome of Cognitive Behavior Therapy for Prevention of Recurrent Depression}, url = {http://dx.doi.org/10.1176/appi.ajp.161.10.1872}, volume = {161}, year = {2004} }

TY - JOUR ID - citeulike:6084251 L3 - citeulike-article-id:6084251 N2 - OBJECTIVE: A paucity of studies use nonpharmacological strategies for preventing recurrence in depression. Cognitive behavior treatment of residual symptoms was found to yield a significantly lower relapse rate than clinical management in recurrent depression at a 2-year follow-up. The objective of this investigation was to provide a 6-year follow-up of cognitive behavior treatment versus clinical management. METHOD: Forty patients with recurrent major depression who had been successfully treated with antidepressant drugs were randomly assigned to either cognitive behavior treatment of residual symptoms (supplemented by lifestyle modification and well-being therapy) or clinical management. In both groups, antidepressant drugs were tapered and discontinued. A 6-year follow-up was undertaken. During this period, no antidepressant drugs were used unless a relapse ensued. RESULTS: Cognitive behavior treatment resulted in a significantly lower relapse rate (40%) at a 6-year follow-up than did clinical management (90%). When multiple recurrences were considered, the group that received cognitive behavior treatment had a significantly lower number of relapses in comparison with the clinical management group. CONCLUSIONS: The results suggest that the sequential use of cognitive behavior treatment after pharmacotherapy may improve the long-term outcome in recurrent depression. A significant proportion of patients with recurrent depression might be able to withdraw from medication successfully and to stay well for at least 6 years with a focused course of psychotherapy. 10.1176/appi.ajp.161.10.1872 IS - 10 JF - Am J Psychiatry EP - 1876 TI - Six-Year Outcome of Cognitive Behavior Therapy for Prevention of Recurrent Depression VL - 161 SP - 1872 KW - cbt KW - depression KW - relapse AU - Fava, Giovanni AU - Ruini, Chiara AU - Rafanelli, Chiara AU - Finos, Livio AU - Conti, Sandra AU - Grandi, Silvana PY - 2004/10/01/ UR - http://dx.doi.org/10.1176/appi.ajp.161.10.1872 ER -