kuhn's drugdiscovery [26 articles] Export Sort

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	Discovery of the first nonpeptidic, small-molecule, highly selective somatostatin receptor subtype 5 antagonists: a chemogenomics approach. [My Copy] J Med Chem, Vol. 50, No. 25. (13 December 2007), pp. 6291-6294. by R. E. Martin, L. G. Green, W. Guba, N. Kratochwil, A. Christ posted to drug drugdiscovery screening by kuhn on 2008-01-18 16:02:24 as
	Keynote review: in vitro safety pharmacology profiling: an essential tool for successful drug development. [My Copy] Drug Discov Today, Vol. 10, No. 21. (1 November 2005), pp. 1421-1433. by S. Whitebread, J. Hamon, D. Bojanic, L. Urban posted to drug drugdiscovery review side_effects by kuhn on 2008-01-14 10:20:32 as
	From Astemizole to a Novel Hit Series of Small-Molecule Somatostatin 5 Receptor Antagonists via GPCR Affinity Profiling [My Copy] J. Med. Chem., Vol. 50, No. 25. (13 December 2007), pp. 6295-6298. by Wolfgang Guba, Luke G. Green, Rainer E. Martin, et al.Olivier Roche, Nicole Kratochwil, Harald Mauser, Caterina Bissantz, Andreas Christ, Martin Stahl posted to activity_profile drugdiscovery gpcr by kuhn on 2008-01-11 13:24:18 as
	Predicting ADME properties and side effects: the BioPrint approach. [My Copy] Curr Opin Drug Discov Devel, Vol. 6, No. 4. (July 2003), pp. 470-480. by C. M. Krejsa, D. Horvath, S. L. Rogalski, et al.J. E. Penzotti, B. Mao, F. Barbosa, J. C. Migeon posted to biospectra drugdiscovery by kuhn on 2007-12-20 15:38:41 as
	Integrating high-content screening and ligand-target prediction to identify mechanism of action. [My Copy] Nat Chem Biol, Vol. 4, No. 1. (January 2008), pp. 59-68. by D. W. Young, A. Bender, J. Hoyt, et al.E. McWhinnie, G. W. Chirn, C. Y. Tao, J. A. Tallarico, M. Labow, J. L. Jenkins, T. J. Mitchison, Y. Feng posted to activity_profile drugdiscovery screening by kuhn on 2007-12-20 14:39:42 as along with 3 people Yanno guhjy kengg
	New uses for old drugs. [My Copy] Nature, Vol. 448, No. 7154. (9 August 2007), pp. 645-646. by Curtis R. Chong, David J. Sullivan posted to activity_profile drug drugdiscovery by kuhn on 2007-11-21 15:58:20 as along with 1 person ekotelnikova
	A conformational restriction approach to the development of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease [My Copy] Bioorganic & Medicinal Chemistry, Vol. 11, No. 20. (October 2003), pp. 4389-4415. by Narihiro Toda, Keiko Tago, Shinji Marumoto, et al.Kazuko Takami, Mayuko Ori, Naho Yamada, Kazuo Koyama, Shunji Naruto, Kazumi Abe, Reina Yamazaki, Takao Hara, Atsushi Aoyagi, Yasuyuki Abe, Tsugio Kaneko, Hiroshi Kogen posted to drug drugdiscovery by kuhn on 2007-11-16 15:07:58 as
	Chemogenomics: an emerging strategy for rapid target and drug discovery [My Copy] Nat Rev Genet, Vol. 5, No. 4. (April 2004), pp. 262-275. by Markus Bredel, Edgar Jacoby posted to chemical drugdiscovery genomics by kuhn on 2007-10-23 16:35:24 as along with 2 people mingzhi Yanno
	A Novel Chemogenomics Knowledge-Based Ligand Design Strategy - Application to G Protein-Coupled Receptors [My Copy] Quantitative Structure-Activity Relationships, Vol. 20, No. 2. (2001), pp. 115-123. by Edgar Jacoby posted to drugdiscovery gpcr by kuhn on 2007-10-23 14:12:55 as
	Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development [My Copy] Nature Reviews Drug Discovery, Vol. 6, No. 9., pp. 721-733. by Jürgen Wess, Richard M. Eglen, Dinesh Gautam posted to drug drugdiscovery by kuhn on 2007-09-03 13:48:39 as along with 2 people and 2 groups guhjy dchughes G4ID Genetics-of-Gambling
	The Many Roles of Computation in Drug Discovery [My Copy] Science, Vol. 303, No. 5665. (19 March 2004), pp. 1813-1818. by William L. Jorgensen posted to drug drugdiscovery review by kuhn on 2007-05-16 10:10:30 as along with 8 people snichols15 dgruiz balicea blackbart ramensky euan onufriev ashaytan
	Relating protein pharmacology by ligand chemistry [My Copy] Nature Biotechnology, Vol. 25, No. 2. (07 February 2007), pp. 197-206. by Michael J. Keiser, Bryan L. Roth, Blaine N. Armbruster, Paul Ernsberger, John J. Irwin, Brian K. Shoichet posted to drug drugdiscovery p prediction similarity by kuhn on 2007-02-16 14:15:57 as along with 10 people psique pablocarb mnishimu ucbcjbm Yanno tjimenez daevans massivemayhem dgront jerome_ucsf_slb
	Knowledge and Intelligence in Drug Design [My Copy] Annual Reports in Medicinal Chemistry, Vol. 41 (2006), pp. 425-437. by Andrew L. Hopkins, Alex Polinsky posted to chemical drug drugdiscovery by kuhn on 2007-02-12 10:39:07 as along with 3 people MarcoAlvarez hkreysa kevinchannon
	New approaches to molecular cancer therapeutics [My Copy] Nat Chem Biol, Vol. 2, No. 12. (December 2006), pp. 689-700. by Ian Collins, Paul Workman posted to cancer drugdiscovery by kuhn on 2006-12-12 08:30:58 as along with 2 people lyndallsarkies Petersarkies
	How many drug targets are there? [My Copy] Nature Reviews Drug Discovery, Vol. 5, No. 12., pp. 993-996. by John P. Overington, Bissan Al-Lazikani, Andrew L. Hopkins posted to drug drugdiscovery review by kuhn on 2006-12-04 09:31:29 as along with 10 people and 1 group BragilMassoud cannin bicko mingzhi higueruelo srp33 ramensky aheilbut gemmalholliday ajaymalik libr
	Systems modeling: a pathway to drug discovery. [My Copy] Curr Opin Chem Biol, Vol. 9, No. 4. (August 2005), pp. 400-406. by P. Rajasethupathy, S. J. Vayttaden, U. S. Bhalla posted to drugdiscovery pathways side_effects systemsbiology by kuhn on 2006-10-02 15:57:56 as along with 4 people snuppepuppan wnpx mmt jdiggans
	Beyond annotation transfer by homology: novel protein-function prediction methods to assist drug discovery. [My Copy] Drug Discov Today, Vol. 10, No. 21. (1 November 2005), pp. 1475-1482. by Y. Ofran, M. Punta, R. Schneider, B. Rost posted to drugdiscovery function prediction by kuhn on 2006-09-21 09:27:51 as along with 3 people and 2 groups jwortman marcius cjeans BioinfoCIPF SGU-CIPF
	An information-intensive approach to the molecular pharmacology of cancer. [My Copy] Science, Vol. 275, No. 5298. (17 January 1997), pp. 343-349. by J. N. Weinstein, T. G. Myers, P. M. O'Connor, et al.S. H. Friend, A. J. Fornace, K. W. Kohn, T. Fojo, S. E. Bates, L. V. Rubinstein, N. L. Anderson, J. K. Buolamwini, W. W. van Osdol, A. P. Monks, D. A. Scudiero, E. A. Sausville, D. W. Zaharevitz, B. Bunow, V. N. Viswanadhan, G. S. Johnson, R. E. Wittes, K. D. Paull posted to bioassay cancer clustering drug drugdiscovery by kuhn on 2006-06-27 12:53:59 as along with 1 person textoris
	Identifying off-target effects and hidden phenotypes of drugs in human cells [My Copy] Nat Chem Biol, Vol. 2, No. 6. (June 2006), pp. 329-337. by Marnie L. Macdonald, Jane Lamerdin, Stephen Owens, et al.Brigitte H. Keon, Graham K. Bilter, Zhidi Shang, Zhengping Huang, Helen Yu, Jennifer Dias, Tomoe Minami, Stephen W. Michnick, John K. Westwick posted to drug drugdiscovery phenotype prediction by kuhn on 2006-06-02 08:28:14 as
	A Pharmacological Map of the PI3-K Family Defines a Role for p110alpha in Insulin Signaling. [My Copy] Cell, Vol. 125, No. 4. (19 May 2006), pp. 733-747. by Z. A. Knight, B. Gonzalez, M. E. Feldman, et al.E. R. Zunder, D. D. Goldenberg, O. Williams, R. Loewith, D. Stokoe, A. Balla, B. Toth, T. Balla, W. A. Weiss, R. L. Williams, K. M. Shokat posted to drugdiscovery similarity by kuhn on 2006-05-23 08:17:24 as
	What do we learn from high-throughput protein interaction data? [My Copy] Expert Rev Proteomics, Vol. 1, No. 1. (June 2004), pp. 111-121. by B. Titz, M. Schlesner, P. Uetz posted to drugdiscovery interaction networks protein by kuhn on 2006-05-02 15:00:38 as along with 3 people maryee grahamc wilbur
	Drug discovery: a historical perspective. [My Copy] Science, Vol. 287, No. 5460. (17 March 2000), pp. 1960-1964. by J. Drews posted to drugdiscovery history by kuhn on 2006-02-14 16:07:10 as along with 12 people and 5 groups jbesnard Yanno BragilMassoud nachtalp Borelli sangeetha joergkurtwegner jdiggans ramensky LamBras srp33 yaredo Bioinformatics Molecular-Modelling Drug-Design Cheminformatics insilicodrug
	Can we rationally design promiscuous drugs? [My Copy] Current Opinion in Structural Biology, Vol. 16, No. 1. (24 February 2006), pp. 127-136. by A. Hopkins, J. Mason, J. Overington posted to drug drugdiscovery promiscuity by kuhn on 2006-02-14 12:25:01 as along with 9 people and 1 group pablocarb pauldobson ubcg08l BragilMassoud apaydin bicko yongzhao ramensky aheilbut TSRI_MGL
	Illuminating drug discovery with biological pathways. [My Copy] FEBS letters, Vol. 579, No. 8. (21 March 2005), pp. 1872-1877. by Gordana Apic, Tijana Ignjatovic, Scott Boyer, Robert B. Russell posted to drug drugdiscovery pathways side_effects systemsbiology by kuhn on 2006-02-08 14:37:32 as along with 8 people Yanno richardbickerton ubcg08l Borelli chad_davis wnpx mikaelhuss renatomilani
	Pharmaceuticals: A new grammar for drug discovery [My Copy] Nature, Vol. 437, No. 7058. (21 September 2005), pp. 491-493. by Mark C. Fishman, Jeffery A. Porter posted to drugdiscovery by kuhn on 2006-01-23 15:47:39 as along with 2 people Vaccine jdiggans
	Innovation: Can cell systems biology rescue drug discovery? [My Copy] Nature Reviews Drug Discovery, Vol. 4, No. 6. (01 June 2005), pp. 461-467. by Eugene C. Butcher posted to drugdiscovery systemsbiology by kuhn on 2006-01-20 13:42:28 as along with 3 people reyez snuppepuppan eweaver

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kuhn's drugdiscovery [26 articles] Export Sort

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