The differing tempo of growth in bone size, mass, and density in girls is region-specific. Export

@article{bass_99_differing, abstract = {The differing tempo and direction of growth of the periosteal and endocortical surfaces, and the differing tempo of growth of the axial and appendicular skeleton, may predispose to regional deficits in bone size, bone mineral content (BMC), and volumetric bone mineral density (vBMD). These traits were measured during 2 years by dual x-ray absorptiometry in 109 girls. By 7 years of age, bone size was approximately 80\% of its maturational peak, and BMC was approximately 40\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\ of its peak. Before puberty, the legs grew more rapidly than the trunk. During puberty, the growth spurt was truncal. Between 7 and 17 years, femoral and lumbar spine BMC increased by 50-150\\ because bone size increased. vBMD increased by 10-30\%. Thus, growth builds a bigger, but only moderately denser, skeleton. Regions growing rapidly, or distant from their peak, may be more severely affected by illness than those growing slowly or nearer completion of growth. Depending on the age of exposure to disease, deficits may occur in limb dimensions (prepuberty), spine dimensions (early puberty), or vBMD by interference with mineral accrual (late puberty). As vBMD is independent of age before puberty, the position of an individual's vBMD in the population distribution is established early in life. Bone fragility in old age may have its foundations in growth.}, address = {Endocrine Unit, Department of Medicine, Austin and Repatriation Medical Centre, University of Melbourne, Melbourne 3084, Australia.}, author = {Bass, S. and Delmas, P. D. and Pearce, G. and Hendrich, E. and Tabensky, A. and Seeman, E.}, citeulike-article-id = {6054801}, journal = {Journal of Clinical Investigation}, keywords = {biomechanics, bone, bone\_mass, growth, sex}, month = {September}, number = {6}, pages = {795--804}, posted-at = {2009-11-01 23:26:23}, priority = {0}, title = {The differing tempo of growth in bone size, mass, and density in girls is region-specific.}, volume = {104}, year = {1999} }

TY - JOUR ID - bass_99_differing L3 - citeulike-article-id:6054801 N2 - The differing tempo and direction of growth of the periosteal and endocortical surfaces, and the differing tempo of growth of the axial and appendicular skeleton, may predispose to regional deficits in bone size, bone mineral content (BMC), and volumetric bone mineral density (vBMD). These traits were measured during 2 years by dual x-ray absorptiometry in 109 girls. By 7 years of age, bone size was approximately 80% of its maturational peak, and BMC was approximately 40\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\ of its peak. Before puberty, the legs grew more rapidly than the trunk. During puberty, the growth spurt was truncal. Between 7 and 17 years, femoral and lumbar spine BMC increased by 50-150\\ because bone size increased. vBMD increased by 10-30%. Thus, growth builds a bigger, but only moderately denser, skeleton. Regions growing rapidly, or distant from their peak, may be more severely affected by illness than those growing slowly or nearer completion of growth. Depending on the age of exposure to disease, deficits may occur in limb dimensions (prepuberty), spine dimensions (early puberty), or vBMD by interference with mineral accrual (late puberty). As vBMD is independent of age before puberty, the position of an individual's vBMD in the population distribution is established early in life. Bone fragility in old age may have its foundations in growth. IS - 6 JF - Journal of Clinical Investigation AD - Endocrine Unit, Department of Medicine, Austin and Repatriation Medical Centre, University of Melbourne, Melbourne 3084, Australia. EP - 804 TI - The differing tempo of growth in bone size, mass, and density in girls is region-specific. VL - 104 SP - 795 KW - biomechanics KW - bone KW - bone_mass KW - growth KW - sex AU - Bass, S AU - Delmas, PD AU - Pearce, G AU - Hendrich, E AU - Tabensky, A AU - Seeman, E PY - 1999/September// ER -