NMR microscopy with isotropic resolution of 3.0 mum using dedicated hardware and optimized methods Export

@article{Weiger2008, abstract = {Nuclear magnetic resonance microscopy at an isotropic resolution of 3.0mum was realized by using dedicated hardware such as RF surface microcoils, a planar triple-axis gradient with 6,500 G/cm, and a static magnetic field of 18.8 T. Purely phase-encoded constant time imaging was used to allow increasing the gradient strength for the suppression of diffusion effects without reducing the signal-to-noise ratio. For this method the relationship between gradient strength and true spatial resolution was investigated, and an empirical formula is provided that is useful for practical applications. The characteristics of the different hardware components were investigated experimentally. Furthermore, microscopic phantom images were acquired and evaluated for their true resolution. It is demonstrated that the use of sufficiently large gradients enables suppressing diffusion-related loss of spatial resolution. {\\copyright} 2008 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 33B: 84-93, 2008}, address = {Bruker Biospin AG, Industriestrasse 26, CH-8117 Faellanden, Switzerland}, author = {Weiger, Markus and Schmidig, Daniel and Denoth, Schimun and Massin, Charles and Vincent, Franck and Schenkel, Michael and Fey, Michael}, citeulike-article-id = {4197309}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/cmr.b.20112}, citeulike-linkout-1 = {http://www3.interscience.wiley.com/cgi-bin/abstract/117955087/ABSTRACT}, doi = {10.1002/cmr.b.20112}, journal = {Concepts in Magnetic Resonance Part B: Magnetic Resonance Engineering}, keywords = {3, micrometer, microscopy, mr}, number = {2}, pages = {84--93}, posted-at = {2009-03-20 11:04:13}, priority = {2}, title = {NMR microscopy with isotropic resolution of 3.0 mum using dedicated hardware and optimized methods}, url = {http://dx.doi.org/10.1002/cmr.b.20112}, volume = {33B}, year = {2008} }

TY - JOUR ID - Weiger2008 L3 - citeulike-article-id:4197309 N2 - Nuclear magnetic resonance microscopy at an isotropic resolution of 3.0mum was realized by using dedicated hardware such as RF surface microcoils, a planar triple-axis gradient with 6,500 G/cm, and a static magnetic field of 18.8 T. Purely phase-encoded constant time imaging was used to allow increasing the gradient strength for the suppression of diffusion effects without reducing the signal-to-noise ratio. For this method the relationship between gradient strength and true spatial resolution was investigated, and an empirical formula is provided that is useful for practical applications. The characteristics of the different hardware components were investigated experimentally. Furthermore, microscopic phantom images were acquired and evaluated for their true resolution. It is demonstrated that the use of sufficiently large gradients enables suppressing diffusion-related loss of spatial resolution. {\\copyright} 2008 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 33B: 84-93, 2008 IS - 2 JF - Concepts in Magnetic Resonance Part B: Magnetic Resonance Engineering AD - Bruker Biospin AG, Industriestrasse 26, CH-8117 Faellanden, Switzerland EP - 93 TI - NMR microscopy with isotropic resolution of 3.0 mum using dedicated hardware and optimized methods VL - 33B SP - 84 KW - 3 KW - micrometer KW - microscopy KW - mr AU - Weiger, Markus AU - Schmidig, Daniel AU - Denoth, Schimun AU - Massin, Charles AU - Vincent, Franck AU - Schenkel, Michael AU - Fey, Michael PY - 2008/// UR - http://dx.doi.org/10.1002/cmr.b.20112 ER -