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An automated technique for statistical characterization of brain tissues in magnetic resonance imaging

by: DL Pham, JL Prince, A Dagher, C Xu
International Journal of Pattern Recognition and Artificial Intelligence, Vol. 11, No. 8. (1997), pp. 1189-1211.


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A procedure for estimating the joint probability density function (pdf) of T 1 , T 2 , and proton spin density (P D ) for gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF) in the brain is presented. The pdf's have numerous applications, including the study of tissue parameter variability in pathology and across populations. The procedure requires a multispectral, spin echo magnetic resonance imaging (MRI) data set of the brain. It consists of five automated steps: 1) preprocess ...


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