Serine/threonine protein phosphatases PP1 and PP2A are key players in apoptosis Export

@article{citeulike:2151627, abstract = {The reversible phosphorylation of proteins controlled by protein kinases and protein phosphatases is a major mechanism that regulates a wide variety of cellular processes. In contrast to C. elegans, recent studies in mammalian cells have highlighted a major role of serine/threonine protein phosphorylation in apoptosis. To illustrate the importance of dephosphorylation processes in apoptosis, this review will focus on recent studies suggesting that the interaction of the serine/threonine protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) with certain regulators of the Bcl-2 family is critically involved in the control of apoptosis.}, author = {Garcia, Alphonse and Cayla, Xavier and Guergnon, Julien and Dessauge, Frederic and Hospital, Veronique and Rebollo, Maria P. and Fleischer, Aarne and Rebollo, Angelita}, booktitle = {Apoptosis: from regulation to infection. Protein phosphatase 'Eminence grise of Apoptosis' web site: http://pp1signature.pasteur.fr}, citeulike-article-id = {2151627}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.biochi.2003.09.004}, citeulike-linkout-1 = {http://www.sciencedirect.com/science/article/B6VRJ-49NPW20-1/2/eff7584fc17a1ad2fd96aee2f1a37278}, doi = {10.1016/j.biochi.2003.09.004}, journal = {Biochimie}, keywords = {apoptosis, pp2a}, month = {August}, number = {8}, pages = {721--726}, posted-at = {2007-12-20 13:30:26}, priority = {2}, title = {Serine/threonine protein phosphatases PP1 and PP2A are key players in apoptosis}, url = {http://dx.doi.org/10.1016/j.biochi.2003.09.004}, volume = {85}, year = {2003} }

TY - JOUR ID - citeulike:2151627 L3 - citeulike-article-id:2151627 N2 - The reversible phosphorylation of proteins controlled by protein kinases and protein phosphatases is a major mechanism that regulates a wide variety of cellular processes. In contrast to C. elegans, recent studies in mammalian cells have highlighted a major role of serine/threonine protein phosphorylation in apoptosis. To illustrate the importance of dephosphorylation processes in apoptosis, this review will focus on recent studies suggesting that the interaction of the serine/threonine protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) with certain regulators of the Bcl-2 family is critically involved in the control of apoptosis. IS - 8 JF - Biochimie EP - 726 TI - Serine/threonine protein phosphatases PP1 and PP2A are key players in apoptosis VL - 85 T2 - Apoptosis: from regulation to infection. Protein phosphatase 'Eminence grise of Apoptosis' web site: http://pp1signature.pasteur.fr SP - 721 KW - apoptosis KW - pp2a AU - Garcia, Alphonse AU - Cayla, Xavier AU - Guergnon, Julien AU - Dessauge, Frederic AU - Hospital, Veronique AU - Rebollo, Maria AU - Fleischer, Aarne AU - Rebollo, Angelita PY - 2003/08// UR - http://dx.doi.org/10.1016/j.biochi.2003.09.004 ER -